STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1264Putative transmembrane sensor protein, no similarity to other bacterial proteins. Best hits to mus musculus and homo sapiens. Domains (LCCL_dom and TIR) are found in proteins (animal and plants) involved in protection against bacterial infection. InterPro: IPR004043 LCCL_dom. IPR000157 TIR. TMHMM reporting 1 transmembrane helices. (423 aa)    
Predicted Functional Partners:
FtsK
Putative cell division protein; DNA translocase ftsK 2. InterPro: FtsK/SpoIIIE family; High confidence in function and specificity.
    
 
 0.830
subC
Subtilisin Savinase precursor, 36% identity to SwissProt; P29600. Has PF00082, Subtilase family;IPR000209, Pept_S8_S53;Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see Trypsin). Structure is an alpha/beta fold containing a 7-stranded parallel beta sheet, order 2314567. PROSITE;) PS00136; SUBTILASE_ASP; 1. PS00137; SUBTILASE_HIS; 1. PS00138; SUBTILASE_SER; 1.
   
 0.827
azo0649
Conserved hypothetical protein. Homology to ebA1795 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebA1795(KEGG)). No domains predicted. No TMHs.
 
 
 0.792
azo2591
Conserved hypothetical secreted protein. Homology to Daro03002418 of Dechloromonas aromatica of 58% (gi|53730135|ref|ZP_00150721.2|(NBCI ENTREZ)). No domains predicted. No TMHs. signal peptide present.
  
     0.690
eglA
Putative endoglucanase precursor; 41% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1. Signal peptide: present; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
    
  0.677
spr1
Putative glucan 1,3-beta-glucosidase; Glucan 13-beta-glucosidase precursor (EC 3.2.1.58) (Exo-13-beta- glucanase).BETA-GLUCANASES PARTICIPATE IN THE METABOLISM OF BETA-GLUCAN THE MAIN STRUCTURAL COMPONENT OF THE CELL WALL. IT COULD ALSO FUNCTION BIOSYNTHETICALLY AS A TRANSGLYCOSYLASE. 33% Glyco_hydro_5. Pfam:PF00150; Cellulase; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
    
  0.677
azo1830
Putative TonB-denpendent receptor; Similar to FepA, an iron regulated outer membrane protein. FepA is a receptor for the siderophore complex ferric enterobactin and for colcins B and D. INVOLVED IN THE INITIAL STEP OF IRON UPTAKE BY BINDING FERRIC ENTEROBACTIN THAT ALLOWS E. COLI TO EXTRACT IRON FROM THE ENVIRONMENT. ilvC: ketol-acid reductoisomerase; Function unclear.
    
 
 0.669
azo2156
TonB-dependent outer membrane receptor involved in the first step of iron internalization and metabolism. A short conserved region so called the tonB-box is present in the sequence. This domain is involved in the interaction of the receptor with the TonB protein. Similar to a E. coli iron(III) dicitrate transport protein fecA precursor. InterPro: TonB-dependent receptor protein arcC: carbamate kinase; Function unclear.
    
 
 0.669
azo3836
Probable Iron-regulated outer membrane TonB-dependent receptor. 35% TonB_receptor.IPR010917; TonB_recept_C.IPR010105; TonB_siderophor. Pfam:PF00593; TonB_dep_Rec; 1. TIGRFAMs:TIGR01783; TonB-siderophor; 1. Signal peptide:present; Function unclear.
    
 
 0.669
fimV2
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear.
  
 
 
 0.661
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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