STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
azo1272Conserved hypothetical secreted protein. Similar to TREMBL:Q9HZ27 (53% identity); TREMBL:Q88RI9 (46% identity); TREMBL:Q8PGP4 (33% identity). Pfam (PF02470): mce related protein. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein. (313 aa)    
Predicted Functional Partners:
azo1274
Putative ABC transporter permease protein; TREMBL:Q88RI7 (56% identity); TREMBL:Q8PGP6 (42% identity). Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting six transmembrane helices; Specificity unclear.
 
 0.994
azo1273
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8PGP5 (60% identity); TREMBL:Q9PDS7 (57% identity). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). Pfam (PF00005): ABC transpor [...]
 
 0.993
azo1271
Conserved hypothetical secreted protein. Homology to pa3214 of P. aeruginosa of 52% (trembl|Q9HZ26). Pfam: DUF330 signal peptide no TMHs; Conserved hypothetical protein.
 
  0.991
azo1691
Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
 
 0.967
azo1692
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7W0L5 (51% identity); TREMBL:Q9A5X8 (46% identity). InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
 
 0.965
azo0807
Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
  
 0.896
azo0806
Conserved hypothetical ABC transporter ATP-binding protein. Homology to rs01335 of R. solanacearum of 67% (trembl|Q8XV69). ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. They are minimally composed of four domains, with two transmembrane domains (TMDs) responsible for allocrite binding and transport and two nucleotide-binding domains (NBDs) responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs. Both NBDs are capable of [...]
  
 0.889
azo0409
Putative anti-sigma factor antagonists (STAS domain protein), STAS. Pfam: PF01740; STAS. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function; Function unclear.
  
 0.836
azo0422
Hypothetical protein; SPROT:P37718: 26% identity, 43% similarity Cellulose synthase operon protein C precursor. Required for maximal bacterial cellulose synthesis. InterPro: STAS domain. The STAS (Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. InterPro:IPR008410; BCSC_C. IPR003921; Cell_synth_C. Pfam:PF05420; BCSC_C; 1. ant_ant_sig: anti-anti-sigma factor No signal peptide present SignalP pr [...]
 
 0.836
azo0811
Conserved hypothetical protein. Homology to rsc2957 of R. solanacearum of 42% (trembl|Q8XV74). Pfam: STAS domain The STAS (after Sulphate Transporter and AntiSigma factor antagonist) domain is found in the C terminal region of Sulphate transporters and bacterial antisigma factor antagonists. It has been suggested that this domain may have a general NTP binding function. no signal peptide no TMHs.
  
 0.815
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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