STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysPPutative sulfate transport system substrate-binding protein; CysP: sulfate/thiosulfate periplasmic binding protein. Sulfate-binding protein precursor (Sulfate starvation-induced protein 2) (SSI2). This protein specifically binds sulfate and is involved in its transmembrane transport. mazG: MazG family protein; High confidence in function and specificity. (336 aa)    
Predicted Functional Partners:
cysW
Sulfate transport system permease protein cysW. Part of the ABC transporter complex cysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane. InterPro: Binding-protein-dependent transport systems inner membrane component uppS: undecaprenyl diphosphate synthase; High confidence in function and specificity.
 
 
 0.999
cysT
Sulfate transport system permease protein probably; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.999
cysA
Putative sulfate transport ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
 
 0.997
cysD
Putative sulfate adenylyltransferase subunit 2; 84% PAPS_reduct. Pfam:PF01507; PAPS_reduct; 1; High confidence in function and specificity.
  
 
 0.974
cysN/C
Putative sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.966
modC2
Putative molybdate transport system ATP-binding protein; 39% AAA_ATPase superfamily. IPR003439; ABC_transporter. IPR008995; MOP_like:molybdenum-pterin binding domain.IPR005116; TOBE. Pfam:PF00005; ABC_tran; 1.PF03459; TOBE; 1; High confidence in function and specificity.
  
 
 0.890
cbl
HTH-type transcriptional regulator cbl (Cys regulon transcriptional activator) Belongs to the LysR family of transcriptional regulators. THIS PROTEIN IS A POSITIVE REGULATOR OF GENE EXPRESSION FOR THE CYSTEINE REGULON. THE INDUCER FOR CYSB IS N-ACETYLSERINE (BY SIMILARITY). ribD_Cterm: riboflavin-specific deami 55% similarity to the HTH-type transcriptional regulator cbl, E. coli SWISSPROT:CBL_ECOLI IPR000847; HTH_LysR. IPR005119; LysR_subst. PF00126; HTH_1; 1. helix-turn-helix PF03466; LysR_substrate; 1. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
       0.768
cysH
Probable phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite.
  
 
 0.725
soxZ
Gene Function; High confidence in function and specificity.
     
  0.684
aapQ
Putative amino acid permease. Homology to aapQ of R. leguminosarum of 35% (sprot|AAPQ_RHILVast). PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR L-AMINO ACIDS. AFFECTS THE UPTAKE AS WELL AS EFFLUX OF THESE AMINO ACIDS. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE SUBSTRATE ACROSS THE MEMBRANE. InterPro: Binding-protein-dependent transport systems inner membrane component (IPR000515) Pfam: Binding-protein -dependent transport system 1 HTH no signal peptide probable 4 TMHs; Family membership.
    
  0.680
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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