STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
copZConserved hypothetical copper chaperon. Homology to copZ of copZ Azoarcus sp. EbN1 of 66%. Pfam: Heavy-metal-associated domain. Proteins that transport heavy metals in micro-organisms and mammals share similarities in their sequences and structures. Tigrfam: TIGR00003: copper-ion-binding protein. No signal peptide. No TMHs; Conserved hypothetical protein. (69 aa)    
Predicted Functional Partners:
copA
CopA: copper transporting P-type ATPase protein,involved in the uptake and metabolism of copper. 44% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR001756; Cu_ATPase.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg.IPR006121; HeavyMe_transpt.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TIGR00003: copper-ion-binding protein. TMHs:8; High confidence in function and specificity.
 
 
 0.988
sodC
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.977
azo2956
Similar to E.coli CopA: copper transporting P-type ATPase protein, involved in the uptake and metabolism of copper(EC 3.6.3.4).Involved in copper transport(By similarity). Putative cation transporting P-type ATPase (EC 3.6.3.-); High confidence in function and specificity.
 
 
 0.962
ccoI
Putative cation-transporting ATPase; 36% ATPase-IB1_Cu.IPR006416; ATPase-IB_hvy.IPR001757; ATPase_E1-E2.IPR005834; Dehal_like_hydro.IPR008250; E1-E2_ATPase_reg. IPR006121; HeavyMe_transpt.IPR000695; H_ATPase.IPR006191; Metal_bind. Pfam:PF00122; E1-E2_ATPase; 1.PF00403; HMA; 1.PF00702; Hydrolase; 1. TMHs:8; Specificity unclear.
 
 
 0.944
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.715
azo1466
Putative superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
     
 0.646
copY
Putative regulatory protein; Heavy metal dependent transcription regulator 2. TRANSCRIPTIONAL REGULATOR INVOLVED IN ACID TOLERANCE. BINDS COPPER (By similarity). It contains a n-terminal dna binding region and a c- terminal metal binding region (by similarity). 35% HTH_MerR.IPR009061; Putativ_DNA_bind. Pfam:PF00376; MerR; 1. TIGR00372: conserved hypothetical protei; High confidence in function and specificity.
  
  
 0.592
fumB
Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.553
azo2950
Multicopper oxidases are enzymes that possess three spectroscopically differentcopper centers. Similar to TREMBL:Q7X4G1 (71% identity); TREMBL:Q8U8U7 (71% identity); TREMBL:Q92ZC7 (70% identity). InterPro (IPR001117): Multicopper oxidase type 1. Pfam (PF00394): Multicopper oxidase. SignalP reporting signal peptide; Function unclear.
  
 
 0.508
rpiA
Putative ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
    0.491
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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