STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carBCarbamoyl-phosphate synthase (glutamine-hydrolyzing) large chain InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity; Belongs to the CarB family. (1075 aa)    
Predicted Functional Partners:
carA
Carbamoyl-phosphate synthase (glutamine-hydrolyzing) small chain; High confidence in function and specificity; Belongs to the CarA family.
 0.999
pyrB
Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
argF
ArgF protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 0.998
argG
ArgG protein; Argininosuccinate synthase, argG. Similar to SWISSPROT:ASSY_NITEU (81%). Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate. InterPro (PF00764): Argininosuccinate synthase InterPro (TIGR00032): Argininosuccinate synthase; High confidence in function and specificity.
 
 0.996
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.986
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
  
 
 0.980
pyrX
Probable dihydroorotase. Homology to pyrC' of P. putida of 44% (sprot|PYRX_PSEPU) This protein tends to appear in a large, multifunctional complex with aspartate transcarbamoylase. It is inactive but is required as a non-catalytic subunit of aspartate transcarbamoylase. InterPro: Dihydroorotase multifunctional complex type (IPR004722); Dihydroorotase (IPR002195) Tigrfam: pyrC_multi: dihydroorotase multifunctional complex type no signal peptide no TMHS; High confidence in function and specificity.
 
 0.975
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 0.961
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.958
gltD
Glutamate synthase (small chain) oxidoreductase; Glutamate synthase [NADPH] precursor (EC 1.4.1.13) (NADPH-GOGAT)small chain. TREMBL:Q8XV67-77% identity, 87% similarity InterPro:IPR006005- One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase (EC: 1.4.1.13) which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+ gid: gid protein Pfam:FAD binding domain,Thi family, 4Fe-4S binding domain,KTN-NAD binding domain, DUF127; High confidence [...]
  
 
 0.939
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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