STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1410ADPribose diphosphatase. ACTIVE ON ADENOSINE(5)TRIPHOSPHO(5)ADENOSINE (AP3A) ADP-RIBOSE NADH ADENOSINE(5)DIPHOSPHO(5)ADENOSINE (AP2A). InterPro: NUDIX hydrolase TIGR00052: conserved hypothetical protein; High confidence in function and specificity. (183 aa)    
Predicted Functional Partners:
nnrD
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...]
 
 
 0.973
prsA
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.898
pgm
Phosphomannomutase/phosphoglucomutase (PMM / PGM). The phosphomannomutase activity produces a precursor for alginate polymerization. This enzyme participates in both the breakdown and synthesis of glucose.Catalytic activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 58% PG/PMM_mutase.IPR005844; PG_PMM_ABAI.IPR005845; PG_PMM_ABAII.IPR005846; PG_PMM_ABAIII.IPR005843; PG_PMM_C. Pfam:PF02878; PGM_PMM_I; 1.PF02879; PGM_PMM_II; 1.PF02880; PGM_PMM_III. PF00408; PGM_PMM_IV; 1; High confidence in function and specificity.
    
  0.892
rhlE1
ATP-dependent RNA helicase; Family membership; Belongs to the DEAD box helicase family.
    
 0.769
rhlE2
Putative ATP-dependent RNA helicase rhlE; Family membership; Belongs to the DEAD box helicase family.
    
 0.769
deaD
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
    
 0.769
rhlE3
Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
    
 0.769
azo0709
Putative exoribonuclease II (EC: 3.1.13.1), RNase R.
 
 
 0.768
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
 0.726
vacB
Exoribonuclease II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.713
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.