STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1430Conserved hypothetical secreted protein. Homology to TdenA01001626 of Thiobacillus denitrificans of 32% (gi|52006684|ref|ZP_00334063.1|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide. no TMHs; Conserved hypothetical protein. (442 aa)    
Predicted Functional Partners:
azo1431
Conserved hypothetical protein; TREMBL: Q8Y0P5 : 81% identity, 90% similarity. Probable Cell division protein ftsH homolog (EC 3.4.24.-). InterPro:IPR003593; AAA_ATPase. IPR003959; AAA_ATPase_centr. Pfam: PF00004; AAA; ATPase family associated with various SMART: SM00382; AAA; Absence of transmembrane helices (TMHMM predicted) NON secretory protein ruvB: Holliday junction DNA helicase Ru; Specificity unclear.
       0.773
azo1429
Conserved hypothetical protein, 63% Identitcal (77% similarity) to TrEMBL;Q8Y0P7,65% identity to TrEMBL;Q7WCK6. Most good homologous hits do not have the same VWA domain represented by this. Has PF05762(IPR008912):VWA domain containing CoxE-like protein;This family is annotated by SMART as containing a VWA type domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria. No Signal peptide or TMH reported present; Function unclear.
       0.768
azo1432
Conserved hypothetical cytochrome c-type protein. Homology to rsc0999 of R. solanacearum of 62% (trembl|Q8Y0P4). Pfam: Cytochrome c signal peptide no TMHs; Conserved hypothetical protein.
       0.553
azo1433
Conserved hypothetical cytochrome c-type protein. Homology to ebA4874 of Azoarcus_EbN1 of 60% (gnl|keqq|eba:ebA4874(KEGG)). Interpro: cytochrome c,classI (IPRoo3088); cytochrome c, class IC (IPR008168). Pfam: cytochrome C. singal peptide. no TMHs; Conserved hypothetical protein.
       0.553
cheV1
Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION; High confidence in function and specificity.
 
     0.534
flgK
Flagellar hook-filament junction protein 1 (HAP1). no signal peptide no TMHs; High confidence in function and specificity.
 
     0.529
azo1674
Conserved hypothetical protein. Homology to CV1155 of Chromobacterium violaceum of 35% (gnl|keqq|cvi:CV1155(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.460
cheV2
Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION; High confidence in function and specificity.
 
     0.452
azo1417
Conserved hypothetical protein. Homology to GSU0904 of Geobacter sulfurreducens of 31% (gnl|keqq|gsu:GSU0904(KEGG)). No domains predicted. No TMHs. No signal peptide.
  
     0.450
flhF
Putative flagellar biosynthesis protein flhF (Flagella associated GTP-binding protein). Necessary for flagellar priosinthesis. May be involved in translocation of the flagellum (by similarity). Belongs to the family of of subunits of the signal recognition particale in bacteria like FtsY, the pilA protein and the flagellar biosynthesis protein flhF. InterPro: AAA ATPase superfamily, GTP-binding signal recognition particell (SRP54) G-domain no signal peptide no TMHs; Family membership.
 
     0.445
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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