STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1431Conserved hypothetical protein; TREMBL: Q8Y0P5 : 81% identity, 90% similarity. Probable Cell division protein ftsH homolog (EC 3.4.24.-). InterPro:IPR003593; AAA_ATPase. IPR003959; AAA_ATPase_centr. Pfam: PF00004; AAA; ATPase family associated with various SMART: SM00382; AAA; Absence of transmembrane helices (TMHMM predicted) NON secretory protein ruvB: Holliday junction DNA helicase Ru; Specificity unclear. (282 aa)    
Predicted Functional Partners:
azo1429
Conserved hypothetical protein, 63% Identitcal (77% similarity) to TrEMBL;Q8Y0P7,65% identity to TrEMBL;Q7WCK6. Most good homologous hits do not have the same VWA domain represented by this. Has PF05762(IPR008912):VWA domain containing CoxE-like protein;This family is annotated by SMART as containing a VWA type domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria. No Signal peptide or TMH reported present; Function unclear.
 
    0.960
azo1430
Conserved hypothetical secreted protein. Homology to TdenA01001626 of Thiobacillus denitrificans of 32% (gi|52006684|ref|ZP_00334063.1|(NBCI ENTREZ)). No domains predicted. Signal P reporting signal peptide. no TMHs; Conserved hypothetical protein.
       0.773
azo1432
Conserved hypothetical cytochrome c-type protein. Homology to rsc0999 of R. solanacearum of 62% (trembl|Q8Y0P4). Pfam: Cytochrome c signal peptide no TMHs; Conserved hypothetical protein.
       0.606
azo1433
Conserved hypothetical cytochrome c-type protein. Homology to ebA4874 of Azoarcus_EbN1 of 60% (gnl|keqq|eba:ebA4874(KEGG)). Interpro: cytochrome c,classI (IPRoo3088); cytochrome c, class IC (IPR008168). Pfam: cytochrome C. singal peptide. no TMHs; Conserved hypothetical protein.
       0.597
adiA
Putative orn/arg/lys decarboxylase. Homology to adiA of E. coli of 37% (sprot|ADIA_ECOLI). This family is composed of ornithine decarboxylases (ODC), arginine decarboxylases (ADC) and lysine decarboxylases (LDC), and belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase domain superfamily (fold I). These enzymes catalyse the decarboxylation of ornithine,arginine, or lysine, respectively using PLP as a co-factor. Pfam: Orn/Lys/Arg decarboxylase no signal peptide no TMHs; Specificity unclear.
    
 
 0.597
norD
Nitric-oxide reductase accessory cytoplasmic protein; Nitric oxide reductase NorD protein. COMPONENT OF THE ANAEROBIC RESPIRATORY CHAIN THAT TRANSFORMS NITRATE TO DINITROGEN (DENITRIFICATION). FUNCTION UNKNOWN BUT ESSENTIAL FOR THE DENITRIFICATION PROCESS. 35% similarity to B. japonicum NorD. TREMBL:Q89QB3 InterPro:IPR002035; VWF_A. Pfam:PF00092; VWA; 1. InterPro:SM00327:von Willebrand factor type A domain SignalP:present. TMHMM: presence of TMHhelix; High confidence in function and specificity.
  
  
 0.424
azo1702
Acyl-CoA dehydrogenase short/branched chain specific mitochondrial precursor (2-methyl branched chain acyl-CoA dehydrogenase) (2-MEBCAD) (2-methylbutyryl-coenzyme A dehydrogenase) (2-methylbutyryl-CoA dehydrogenase). Has greatest activity toward short branched chain acyl- CoA derivative such as (s)-2-methylbutyryl-CoA isobutyryl-CoA and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl- CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this [...]
  
     0.420
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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