STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flhCFlagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (184 aa)    
Predicted Functional Partners:
flhD
Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
 0.999
motB2
Flagellar motor protein MotB (Chemotaxis motB protein. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall. Pfam: OmpA family no signal peptide probable 1 TMHs; High confidence in function and specificity.
 
  
 0.931
motA2
Flagellar motor protein MotA (Chemotaxis motA protein). Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). signal peptide probable 4 TMHs; High confidence in function and specificity.
 
    0.897
flgA
Flagella basal body P-ring formation protein flgA precursor. Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a chaperon protein for the P-ring assembly (by similarity). signal peptide no TMHs; High confidence in function and specificity.
  
  
 0.732
fliL
Putative flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.711
fliJ
Flagellar fliJ protein. FLAGELLAR PROTEIN THAT AFFECTS CHEMOTACTIC EVENTS. Might have a chaperon-like activity InterPro: Flagellar FliJ protein no signal peptide no TMHs; Family membership.
  
   
 0.707
azo1108
Flagellar motor protein MotA (Chemotaxis motA protein). Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity). Pfam: MotA/TolQ//ExbB proton channel family signal peptide probable 4 TMHs; High confidence in function and specificity.
  
    0.673
fliA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.571
cheW2
Positive regulator of CheA protein activity,; High confidence in function and specificity.
 
    0.570
azo0281
Outer membrane protein A precursor. Homology with hypothetical transmembrane protein and probable outer membrane protein of 56% as well as with motB (flagellar motor protein B) from amino acid 84 of 34%. Pfam: OmpA no signal peptide probable 1 TMH; Conserved hypothetical protein.
  
  
 0.563
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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