Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
exbD4Putative biopolymer transport exbD2 protein. Homology to exbD2 of V. choloera of 31% ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: Biopolymer transport protein ExbD/TolR Pfam: Biopolymer transport protein ExbD/TolR no signal peptide probable 1 TMH; Family membership. (140 aa)    
Predicted Functional Partners:
exbB3
Conserved hypothetical biopolymer transport protein ExbB. Homology to exbB of B. pertussis. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family no signal peptide probable 3 TMHS; Family membership.
 
 
 0.984
tolQ
Translocation protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.878
lpxK
Probable tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
     0.846
kdsB
Probable 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
     0.838
exbB2
Probable biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 50% ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro: MotA/TolQ/ExbB proton channel family Pfam: MotA/TolQ/ExbB proton channel family no signal peptide no TMHs; Family membership.
 
 
 0.820
ycaR
Conserved hypothetical protein; Putative inner membrane protein [ycaR], 66% identity (85% similarity) to SwissProt;P75844(E.coli) and 65% identity to TrEMBL;Q7CQT7. Has PF03966:Protein of unknown function (DUF343);This family of short proteins have no known function. The bacterial members are about 60-70 amino acids in length and the eukaryotic examples are about 120 amino acids in length. The C terminus contains the strongest conservation. Signal Peptide or TMH not present; Function unclear; Belongs to the UPF0434 family.
       0.817
exbB1
Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 35%. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. PFam: MotA/TolQ/ExbB proton channel family signals peptide most probable 4 TMHs; Family membership.
 
 
 0.812
exbB4
Putative biopolymer transport protein ExbB. Homology to exbB of B. pertussis of 36%. ExbB is part of the TonB-dependent transduction complex. The tonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. Pfam: MotA/TolQ/ExbB proton channel family signal peptide most probable 4TMHs; Family membership.
 
 
 0.806
azo0708
Conserved hypothetical secreted protein. Homology to ne1626 of N. europaea of 46% (trembl|Q82U75) no domains predicted signal peptide TMH in signal peptide; Conserved hypothetical protein.
 
 
 0.760
azo2632
Conserved hypothetical membrane protein. Homology to PA1924 of P. aeruginosa of 43% (trembl|Q9I2I0(SRS)). No domains predicted. no signal peptide. probable 3TMHS; Conserved hypothetical protein.
  
 
 0.663
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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