| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo0857 | azo1483 | azo0857 | azo1483 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | 0.571 |
| azo0857 | gmk | azo0857 | azo3953 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.583 |
| azo0857 | guaA | azo0857 | azo1581 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.827 |
| azo0857 | guaB | azo0857 | azo1580 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.787 |
| azo0857 | nucH | azo0857 | azo1484 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | Putative extracellular nuclease. Homology to nucH of A. hydrophila of 33% (trembl|Q44070) Tigrfam: xth: exodeoxyribonuclease III (xth) Pfam: Endonuclease/ Exonuclease/ Phoshatase family singal peptide no TMHs; Family membership. | 0.499 |
| azo0857 | purH | azo0857 | azo2894 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] InterPro: AICARFT/IMPCHase bienzyme; High confidence in function and specificity. | 0.590 |
| azo0857 | surE | azo0857 | azo1087 | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.853 |
| azo1483 | azo0857 | azo1483 | azo0857 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | 0.571 |
| azo1483 | gmk | azo1483 | azo3953 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.638 |
| azo1483 | guaA | azo1483 | azo1581 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.777 |
| azo1483 | guaB | azo1483 | azo1580 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.851 |
| azo1483 | nucH | azo1483 | azo1484 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Putative extracellular nuclease. Homology to nucH of A. hydrophila of 33% (trembl|Q44070) Tigrfam: xth: exodeoxyribonuclease III (xth) Pfam: Endonuclease/ Exonuclease/ Phoshatase family singal peptide no TMHs; Family membership. | 0.978 |
| azo1483 | purH | azo1483 | azo2894 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)] InterPro: AICARFT/IMPCHase bienzyme; High confidence in function and specificity. | 0.690 |
| azo1483 | surE | azo1483 | azo1087 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | Phosphoric-monoester phosphohydrolase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.693 |
| azo1483 | tmk | azo1483 | azo1595 | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.734 |
| azo1485 | nucH | azo1485 | azo1484 | Conserved hypothetical membrane protein. Homology ebA4071 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA4071(KEGG)). Has PF06930, Protein of unknown function (DUF1282); IPR009698; This family consists of several hypothetical proteins of around 200 residues in length. The function of this family is unknown although a number of family members are thought to be putative membrane proteins. no signal peptide. 5 TMHs; Conserved hypothetical protein. | Putative extracellular nuclease. Homology to nucH of A. hydrophila of 33% (trembl|Q44070) Tigrfam: xth: exodeoxyribonuclease III (xth) Pfam: Endonuclease/ Exonuclease/ Phoshatase family singal peptide no TMHs; Family membership. | 0.489 |
| gmk | azo0857 | azo3953 | azo0857 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 38% PfkB.Family of carbohydrate kinases Pfam:PF00294; PfkB; 1; Specificity unclear. | 0.583 |
| gmk | azo1483 | azo3953 | azo1483 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative 5'-nucleotidase Has Signal Peptide. Has PF02872, 5'-nucleotidase, C-terminal domain; IPR008334, 5'-Nucleotdase_C; 5'-nucleotidases are enzymes that catalyze the hydrolysis ofphosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules. 5'-nucleotidase is a ubiquitous enzyme found in a wide variety of species and which occurs in different cellular locations. The extracellular 5'-nucleotidase from mammals and electric ray isozyme is a homodimeric disulphide-bonded glycoprotein attached to the membrane by a GPI-anchor, and requires zinc for its [...] | 0.638 |
| gmk | guaA | azo3953 | azo1581 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.983 |
| gmk | guaB | azo3953 | azo1580 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.778 |