STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1485Conserved hypothetical membrane protein. Homology ebA4071 of Azoarcus sp. EbN1 of 61% (gnl|keqq|eba:ebA4071(KEGG)). Has PF06930, Protein of unknown function (DUF1282); IPR009698; This family consists of several hypothetical proteins of around 200 residues in length. The function of this family is unknown although a number of family members are thought to be putative membrane proteins. no signal peptide. 5 TMHs; Conserved hypothetical protein. (229 aa)    
Predicted Functional Partners:
fimV2
Putative type 4 pilus biogenesis; In Pseudomonas aeruginosa, FimV is probable involved in remodelling of the peptidoglycan layer to enable assembly of the type IV fimbrial structure and machinery. And it is also required for twitching motility. Similar to trembl|O87015 (26%). Pfam (PF05489): Phage Tail Protein X SignalP reporting Signal peptide; Function unclear.
  
     0.731
azo0621
Conserved hypothetical secreted protein. Homology to ebA1833 of Azoarcus sp. EbN1 of 48% (gnl|keqq|eba:ebA1833(KEGG)). No domains predicted. Signal peptide Present. No TMH present; Conserved hypothetical protein.
  
     0.614
azo2202
Probable DNA polymerase III, epsilon subunit,23% Identity to TrEMBL;Q8KDK8. Has EXOIII,SMART;SM00479;IPR006054, DnaQ;This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III. Ribonuclease T is responsible for the end-turnover of tRNA,and removes the terminal AMP residue from uncharged tRNA. DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria, and also exhibits 3' to 5' exonuclease activity.
  
     0.602
azo1496
Conserved Hypothetical protein Signal Peptide present. Has Prosite PS00380; RHODANESE_1; Rhodanese (thiosulfate sulfurtransferase) (EC 2.8.1.1)is an enzyme which catalyzes the transfer of the sulfane atom of thiosulfate to cyanide, to form sulfite and thiocyanate. In vertebrates, rhodanese is a mitochondrial enzyme of about 300 amino-acid residues involved in forming iron-sulfur complexes and cyanide detoxification. A cysteine residue takes part in the catalytic mechanism.
  
     0.600
azo1494
Similarity to hypothetical protein in C. violaceum.
  
     0.550
azo2969
Conserved hypothetical secreted protein. Homology to ebA582 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA582(KEGG)). No domains predicted. Signal P reporting signal peptide. No TMHs; Conserved hypothetical protein.
  
     0.547
azo1495
Conserved hypothetical protein. Homology to CV0860 of Chromobacterium violaceum of 50% (trembl: Q7NZR1). No domains predicted. No TMHs. No signal peptide.
  
     0.545
azo1836
Hypothetical protein sharing 76% similarity(61% identity) with Hypothetical protein [Thauera aromatica]TrEMBl O87938. Has pfam06980, DUF1302 domain,Protein of unknown function (DUF1302). This family contains a number of hypothetical bacterial proteins of unknown function that are approximately 600 residues long. Most family members seem to be from Pseudomonas.(IPR010727) No Signal peptide or TMH being reported to be present; Function unclear.
  
     0.531
azo0364
Conserved hypothtical membrane protein. Homology to rc03284 of R. solanacearum of 35% (trembl|Q8Y2L8(SRS) Has a weak hit to PF04892(IPR006976;vanZ)in Smart:This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases. VanZ confers low-level resistance to the glycopeptide antibiotic teicoplanin (Te). Analysis of cytoplasmic peptidoglycan precursors, accumulated in the presence of ramoplanin,showed that VanZ-mediated Te resistance does not involve incorporation of a substituent of D-alanine into the peptidoglycan precursors. no signal p [...]
  
     0.527
azo2092
Conserved hypothetical membrane protein. Homology to ebA1234 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA1234(KEGG)). no domains predicted. no signal peptide. 1 TMH; Conserved hypothetical protein.
  
     0.499
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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