STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1486Conserved hypothetical signaling protein. Homology to TdenA01000705 of Thiobacillus denitrificans of 61% (gi|52008401|ref|ZP_00335778.1|(NBCI ENTREZ)). Pfam: PF01590 GAF domain. PF00563 EAL domain. No signal peptide. No TMHs; Conserved hypothetical protein. (399 aa)    
Predicted Functional Partners:
azo2408
Hypothetical sensor protein.
 
 0.890
azo0426
GGDEF/PAS-domain containing protein.
 
 0.882
azo2829
GGDEF/PAS/PAC-domain containing protein.
 0.869
azo0450
PAS/PAC/GGDEF-domain containing protein,implicating involvement into signalling processes. Similarity to TREMBL: trembl|Q98JA6 (30% Rhizobium loti,hypothetical protein mlr2027) InterPro: IPR000160 GGDEF. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. Pfam: PF00990 GGDEF. SMART: SM00086 PAC. SM00091 PAS. TIGRFAM: TIGR00254 GGDEF. TIGR00229 sensory_box.
 0.864
azo3809
Conserved hypothetical membrane protein.
 0.859
ydaM
Hypothetical response regulator, TREMBL: trembl|Q7MSI2 (24% Wolinella succinogenes, hypothetical protein ws0414) InterPro: IPR001610 PAC. IPR000014 PAS. IPR001789 Response_reg. IPR000160 GGDEF. Pfam: PF00990 GGDEF domain. PF00072 Response_reg. PF00785 PAC. PF00989 PAS. TIGRFAM: TIGR00254 putative diguanylate cyclase (GGDEF) domain. TIGR00229 PAS domain S-box; Conserved hypothetical protein.
 0.857
azo0336
PAS/PAC/GGDEF-domain containing protein, suggesting involvement into signalling processes. Similarity to SWISSPROT: sprot|YDAM_ECOLI (24% Escherichia coli, hyp. protein) / TREMBL: trembl|Q887F0 (59% Pseudomonas syringae, hyp. protein) Pfam: PF00990 GGDEF domain. This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. The function of this domain is unknown, however it has been shown to be homologous to the adenylyl cyclase catalytic domain. This prediction correlates with the functional information available on two GGDEF-containing proteins, namel [...]
 0.855
azo2712
GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein.
 
 0.850
azo2866
GGDEF/PAS/PAC-domain containing protein.
 
 0.840
azo3381
Hypothetical signaling protein.
 
0.840
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.