STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1489Hypothetical protein CT2219. SPROT:Q8KAE4: 65% identity; 78% similarity. TREMBL:Q7NS63: 60% identity, 72% similarity putative ACR related to the C-terminal domain of histone macroH2A1 This domain is found in a number of protein associated with DNA and/or RNA unwinding InterPro; IPR002589; A1pp. Pfam; PF01661; A1pp; 1. SMART; SM00506; A1pp non-secretory protein with no signal peptide (SignalP predicted). No transmembrane helices (TMHMM predicted); Function unclear. (172 aa)    
Predicted Functional Partners:
azo1490
Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein.
       0.510
divK
Probable polar differentiation response regulator,; Family membership.
       0.509
divJ
Putative histidine protein kinase,; Specificity unclear.
       0.509
npd1
Putative NAD-dependent deacetylase (EC 3.5.1.-) (Regulatory protein SIR2 homolog). Modulates the activities of several enzymes which are inactive in their acetylated form. Similar to SWISSPROT: sprot|NPD_AERPE (27% Aeropyrum pernix, NpdA or aq_2170) Pfam: PF02146 Sir2 family; High confidence in function and specificity.
   
 0.460
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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