STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
yggHtRNA (guanine-N(7)-)-methyltransferase, 29% identity to SwissProt;Q8EBX8. SwissProt;Q8Y1I7(25% Identity),Q8FE22(25% identity). Has PF02390,Methyltransf_4,Putative methyltransferase;IPR003358; This is a family of putative methyltransferases. The aligned region contains the GXGXG S-AdoMet binding site suggesting a putative methyltransferase activity. (231 aa)    
Predicted Functional Partners:
trmB
Conserved hypothetical tRNA (guanine-N7-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
  0.905
azo3706
Conserved hypothetical protein; Similar to TREMBL:Q89RW7 (50% identity,64% similarity); TREMBL:Q88IS2 (49% identity). InterPro (IPR000051); SAM (and some other nucleotide) binding motif.
  
 0.871
azo3711
Conserved hypothetical protein; Similar to SWISSPROT:P39367 (68% identity),TREMBL:Q8Z1C8 (66% identity).
  
 0.871
serS
SerS protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
 0.849
dusC
Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.
  
 
 0.800
azo1525
Conserved hypothetical protein. Homology to PA3209 of Pseudomonas aeruginosa of 43% (trembl:Q9HZ31). Has PF03692, Uncharacterised protein family (UPF0153); IPR005358;This family of proteins contain 8 conserved cysteines that may form a metal binding site. The function of these proteins is unknown but might be an Fe-S cluster as part of an oxidoreductase complex. No signal peptide. No TMHs.
       0.789
azo1524
Conserved hypothetical protein. Homology to ct227 of C. tepidum of 32% (trembl|Q8KA93). Pfam: SEC-C motif This motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain. no TMHs.
       0.774
azo2636
Putative CbbY family protein; TREMBL:Q7MF75: 35% identity; 50% similarity. IPR006323; Phosphonoacetaldehyde hydrolase IPR010976; Beta-phosphoglucomutase hydrolase This group of sequences represent part of one structural subfamily of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases (IPR005834). The superfamily is defined by the presence of three short catalytic motifs. Hypothetical protein yhcW. InterPro:IPR006402; HAD-SF-IA-v3. IPR005833; Halogease/hydrolase. Pfam: PF00702; Hydrolase Absence of signal peptide (Signal P predicted) and transmembrane helices [...]
    
  0.739
azo3477
Conserved hypothetical protein; Predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.
    
  0.717
truB
tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.703
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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