ptsp protein (Azoarcus sp. BH72) - STRING interaction network

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ptsp

Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear. (452 aa)

Predicted Functional Partners:

azo2450

0.959

azo1537

0.956

azo1817

0.921

azo3685

0.877

azo3381

0.871

azo2457

0.870

azo0694

0.850

dctS

0.850

nifL

0.845

azo0624

0.845

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
azo0624	azo0694	azo0624	azo0694	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Putative hybrid sensor and regulator protein,; Specificity unclear.	0.965
azo0624	azo1817	azo0624	azo1817	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl\|keqq\|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]	0.994
azo0624	azo2450	azo0624	azo2450	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Putative two-component system sensor protein,; Function unclear.	0.990
azo0624	azo2457	azo0624	azo2457	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Putative sensory box histidine kinase,; Function unclear.	0.987
azo0624	azo3381	azo0624	azo3381	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Hypothetical signaling protein.	0.989
azo0624	azo3685	azo0624	azo3685	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.	0.990
azo0624	dctS	azo0624	azo0918	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Two-component sensor kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.	0.678
azo0624	ptsp	azo0624	azo1538	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear.	0.845
azo0694	azo0624	azo0694	azo0624	Putative hybrid sensor and regulator protein,; Specificity unclear.	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	0.965
azo0694	azo1817	azo0694	azo1817	Putative hybrid sensor and regulator protein,; Specificity unclear.	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl\|keqq\|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]	0.996
azo0694	azo2450	azo0694	azo2450	Putative hybrid sensor and regulator protein,; Specificity unclear.	Putative two-component system sensor protein,; Function unclear.	0.995
azo0694	azo2457	azo0694	azo2457	Putative hybrid sensor and regulator protein,; Specificity unclear.	Putative sensory box histidine kinase,; Function unclear.	0.996
azo0694	azo3381	azo0694	azo3381	Putative hybrid sensor and regulator protein,; Specificity unclear.	Hypothetical signaling protein.	0.995
azo0694	azo3685	azo0694	azo3685	Putative hybrid sensor and regulator protein,; Specificity unclear.	Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.	0.995
azo0694	dctS	azo0694	azo0918	Putative hybrid sensor and regulator protein,; Specificity unclear.	Two-component sensor kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.	0.987
azo0694	nifL	azo0694	azo0518	Putative hybrid sensor and regulator protein,; Specificity unclear.	Nitrogen fixation regulatory protein (EC 2.7.3.-). Required for the inhibition of nifA activity in response to oxygen and low level of fixed nitrogen. Similar to SWISSPROT: sprot\|NIFL_AZOVI (41% Azotobacter vinelandii,nitrogen fixation regulatory protein (EC 2.7.3.-), NifL) InterPro: IPR003661 His_kinA_N. The histidine kinase A (phosphoacceptor) N-terminal domain is a dimerisation and phosphoacceptor domain of histidine kinases. It has been found in bacterial sensor protein/histidine kinases. IPR000014 PAS. PAS domains are involved in many signalling proteins where they are used as a s [...]	0.951
azo0694	ptsp	azo0694	azo1538	Putative hybrid sensor and regulator protein,; Specificity unclear.	Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear.	0.850
azo1537	ptsp	azo1537	azo1538	Conserved hypothetical protein. Homology to Raeut03004638 of Ralstonia eutropha of 37% (gi\|45515835\|ref\|ZP_00167389.1\|(NBCI ENTREZ)). No domains predicted. No signal peptide. No TMHs.	Putative phosphoenolpyruvate-protein phosphotransferase,; Function unclear.	0.956
azo1817	azo0624	azo1817	azo0624	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl\|keqq\|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]	PAS/PAC-domain containing protein, shows good similarity only to parts of other proteins (mostly sensor kinases). This suggests that there normally should be a kinase domain and therefore the protein is not complete. Also the downstream response regulator gives a hint for this suggestion. InterPro: IPR000014 PAS_domain. IPR001610 PAC motif. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal peptide. TMHMM reporting 2 transmembrane helices.	0.994
azo1817	azo0694	azo1817	azo0694	Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl\|keqq\|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]	Putative hybrid sensor and regulator protein,; Specificity unclear.	0.996