Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mobB1Molybdopterin-guanine dinucleotide biosynthesis protein B. may bind the guanine nucleotide required for the synthesis of molybdopterin guanine dinucleotide. mobB: molybdopterin-guanine dinucleotide; High confidence in function and specificity. (164 aa)    
Predicted Functional Partners:
mobA
Probable molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
 0.982
moeA1
Molybdopterin cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.971
moeA2
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 0.939
moaE
Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor subunit 2 (MPT synthase subunit 2) (Molybdopterin synthase subunit 2). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group; High confidence in function and specificity.
 
 
 0.923
moaD
Molybdopterin converting factor subunit 1 (MPT synthase subunit 1) (Molybdopterin synthase subunit 1) (Molybdenum cofactor biosynthesis protein D). Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur atoms are provided by the active form of the small subunit whose activation involves the acquisition of sulfur and the activity of moeB/chlN; High confidence in function and specificity.
 
 
 0.870
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 0.862
fdhD
Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  0.792
fdhA1
Probable formate dehydrogenase (NADP+), alpha subunit. Homology to fdh1A of M. extorquens of 60% (trembl|Q8KTI7). InterPro: Prokaryotic molybdopterin oxidoreductases (IPR006655); Respiratory-chain NADH dehydrogenase 75 kD subunit (IPR000283); Ferredoxin (IPR001041); 4Fe-4S ferredoxin, iron-sulfur binding domain (IPR001450) Pfam: 2Fe-2S iron-sulfur cluster binding domain; 4Fe-2S binding doami; Molybdopterin oxidase; Molybdopterin dinucloetide binding no signal peptide no TMHs; High confidence in function and specificity; Belongs to the prokaryotic molybdopterin-containing oxidoreductase [...]
 
     0.644
yoaA
Probable ATP-dependent helicase,; Family membership.
       0.627
azo3487
Conserved hypothetical protein. Homology to BPP1929 of B.parapertussis of 34% (trembl:34%). No signal peptide or TMH reported present. No domains predicted.
 
 0.610
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.