Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ppiDPutative peptidyl-prolyl cis-trans isomerase. Homology to ppiD of E. coli of 23% (sprot|PPID_ECOLI). PPIASES ACCELERATE THE FOLDING OF PROTEINS. SEEMS TO BE INVOLVED IN THE FOLDING OF OUTER MEMBRANE PROTEINS. InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain probable 1 TMH no signal peptide; Family membership. (631 aa)    
Predicted Functional Partners:
oma
Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
 0.729
cpoB
Conserved hypothetical secreted protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
   0.705
nlpB
Putative lipoprotein. Homology to nlpB of E. coli of 20% (sprot|NLPB_ECOLI) This family consists of a number of bacterial lipoproteins often known as NlpB or DapX. This lipoprotein is detected in outer membrane vesicles in Escherichia coli and appears to be nonessential. Pfam: NlpB/DapX lipoprotein singal peptide no TMHs; Family membership.
  
 
 
 0.626
comL
Probable competence lipoprotein precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 
 0.604
bamB
Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
 
 0.541
hflK
Putative Hflk protein; HflC and HflK could encode or regulate a protease.
 
    0.535
azo1567
GGDEF/EAL-domain containing protein.
       0.524
yidC
Propable 60 Kd inner-membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.518
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.503
azo0810
Conserved hypothetical secreted protein. Similar to TREMBL:Q82SF8 (54% identity); TREMBL:Q8XV73 (42% identity); TREMBL:Q7VSZ6 (40% identity). SignalP reporting signal peptide. no TMHs; Conserved hypothetical protein.
  
     0.496
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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