| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo1591 | azo1592 | azo1591 | azo1592 | Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present. | Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide. | 0.799 |
| azo1591 | azo1593 | azo1591 | azo1593 | Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present. | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | 0.798 |
| azo1592 | azo1591 | azo1592 | azo1591 | Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide. | Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present. | 0.799 |
| azo1592 | azo1593 | azo1592 | azo1593 | Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide. | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | 0.781 |
| azo1593 | azo1591 | azo1593 | azo1591 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Conserved hypothetical protein. Homology to GSU0792 of G.sulfurreducens of 50% (gsu:GSU0792(KEGG)) Has PF05742(IPR008551);Protein of unknown function (DUF833);This family is found in eukaryotes, prokaryotes and viruses and has no known function. P54797 has been found to be expressed during early embryogenesis in mice. No signal peptide or TMH present. | 0.798 |
| azo1593 | azo1592 | azo1593 | azo1592 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Conserved hypothetical protein. Homology to ebD92 of Azoarcus sp. EbN1 of 46% (gnl|keqq|eba:ebD92(KEGG)). No domains predicted. No TMHs. No signal peptide. | 0.781 |
| azo1593 | azo3201 | azo1593 | azo3201 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.673 |
| azo1593 | azo3295 | azo1593 | azo3295 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086). | 0.707 |
| azo1593 | cyaY | azo1593 | azo3652 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.796 |
| azo1593 | erpA | azo1593 | azo2758 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters. | 0.908 |
| azo1593 | gltD | azo1593 | azo3641 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Glutamate synthase (small chain) oxidoreductase; Glutamate synthase [NADPH] precursor (EC 1.4.1.13) (NADPH-GOGAT)small chain. TREMBL:Q8XV67-77% identity, 87% similarity InterPro:IPR006005- One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase (EC: 1.4.1.13) which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+ gid: gid protein Pfam:FAD binding domain,Thi family, 4Fe-4S binding domain,KTN-NAD binding domain, DUF127; High confidence [...] | 0.726 |
| azo1593 | hesB | azo1593 | azo0554 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | HesB/yadR/yfhF family protein, 45% identity to TrEMBL;Q9KJL2,Q6HRJ0. SwissProt;P37026(41% identity) Has PF01521, HesB-like domain;IPR000361, HesB_yadR_yfhF;This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confi [...] | 0.903 |
| azo1593 | nifU | azo1593 | azo0553 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Probable nitrogen fixation protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. | 0.897 |
| azo1593 | yfhF | azo1593 | azo2014 | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | Putative regulatory Protein yfhF, 72% identity (82% similarity) to TrEMBL;P36539 of E.coli. Has PF01521, HesB-like domain;(IPR000361, HesB_yadR_yfhF); This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confidence [...] | 0.920 |
| azo3201 | azo1593 | azo3201 | azo1593 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Conserved hypothetical protein aminomethyltransferase. Homology to ne1514 of N. europaea of 37% (trembl|Q82UH2) InterPro: Glycine cleavage T-protein (aminomethyl transferase) Tigrfam: gcvT: glycine cleavage system T protein Pfam: Glycine cleavage T-protein This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) which catalyses the catabolism of glycine. The T-protein is an aminomethyl transferase that catalyses the following reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + d [...] | 0.673 |
| azo3201 | azo3295 | azo3201 | azo3295 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Putative Cytochrome aa3 oxidase assembly protein,42% Identity to TrEMBL;Q7P0G1, Q62F60. Has PF02628,Cytochrome oxidase assembly protein; IPR003780,COX15_CtaA; This is a family of integral membrane proteins. CtaA is required for cytochrome aa3 oxidase assembly in Bacillus subtilis. COX15 is required for cytochrome c oxidase assembly in yeast (P40086). | 0.575 |
| azo3201 | cyaY | azo3201 | azo3652 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Putative CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.720 |
| azo3201 | erpA | azo3201 | azo2758 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters. | 0.703 |
| azo3201 | gltD | azo3201 | azo3641 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | Glutamate synthase (small chain) oxidoreductase; Glutamate synthase [NADPH] precursor (EC 1.4.1.13) (NADPH-GOGAT)small chain. TREMBL:Q8XV67-77% identity, 87% similarity InterPro:IPR006005- One pathway for the assimilation of ammonia and glutamate biosynthesis involves glutamate synthase (EC: 1.4.1.13) which transfers the amide group of glutamine to 2-oxoglutarate to yield two molecules of glutamate. 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH + H+ gid: gid protein Pfam:FAD binding domain,Thi family, 4Fe-4S binding domain,KTN-NAD binding domain, DUF127; High confidence [...] | 0.585 |
| azo3201 | hesB | azo3201 | azo0554 | Putative iron sulfur binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | HesB/yadR/yfhF family protein, 45% identity to TrEMBL;Q9KJL2,Q6HRJ0. SwissProt;P37026(41% identity) Has PF01521, HesB-like domain;IPR000361, HesB_yadR_yfhF;This family includes HesB which may be involved in nitrogen fixation; the hesB gene is expressed only under nitrogen fixation conditions. Other members of this family include various hypothetical proteins of which P46847 and NP31774 also contains NifU-like domains NifU which is also involved in nitrogen fixation. In the gram-negative soil bacterium Rhizobium etli, the hesB-like gene iscN is required for nitrogen fixation; High confi [...] | 0.697 |
