| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FtsA | mltG | azo0888 | azo1594 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.683 |
| FtsA | mrcA | azo0888 | azo3651 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Probable penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin- insensitive transglycosylase (EC 2.4.2.-) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.-.-) (DD-transpeptidase)]. Homology to mrcA of N. meningitides of 47% (sprot|PBPA_NEIMA(SRS)) Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (By sim [...] | 0.562 |
| FtsA | mtgA | azo0888 | azo0706 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Probable monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.407 |
| FtsA | pbpA | azo0888 | azo0177 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.915 |
| ank1 | azo1598 | azo1599 | azo1598 | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | 0.799 |
| ank1 | holB | azo1599 | azo1596 | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | 0.773 |
| ank1 | mltG | azo1599 | azo1594 | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.757 |
| ank1 | pilZ | azo1599 | azo1597 | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875; This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown. | 0.725 |
| ank1 | tmk | azo1599 | azo1595 | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.741 |
| aroE | mltG | azo0707 | azo1594 | AroE protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.651 |
| aroE | mtgA | azo0707 | azo0706 | AroE protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Probable monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.825 |
| azo1598 | ank1 | azo1598 | azo1599 | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | 0.799 |
| azo1598 | holB | azo1598 | azo1596 | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | 0.827 |
| azo1598 | mltG | azo1598 | azo1594 | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.900 |
| azo1598 | pilZ | azo1598 | azo1597 | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875; This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown. | 0.769 |
| azo1598 | tmk | azo1598 | azo1595 | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.770 |
| holB | ank1 | azo1596 | azo1599 | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...] | 0.773 |
| holB | azo1598 | azo1596 | azo1598 | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | Putative deoxyribonuclease yabD (EC 3.1.21.-). InterPro: Uncharacterized protein family UPF0006. TIGR00010: deoxyribonuclease TatD family; Specificity unclear. | 0.827 |
| holB | mltG | azo1596 | azo1594 | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.884 |
| holB | pilZ | azo1596 | azo1597 | DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity. | Type IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875; This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown. | 0.842 |
