STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilZType IV pilus biogenesis protein PilZ, 56% identity to TrEMBL;Q87YH3, Q8PBU4. Has PF07238, Type IV pilus assembly protein PilZ; IPR009875; This family consists of several bacterial type IV pilus assembly proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown. (123 aa)    
Predicted Functional Partners:
azo0652
Conserved hypothetical GGDF domain protein. Homology to CV0310 of Chromobacterium violaceum of 34% (trembl|Q7P1A3). Has IPR003660_HAMP,SMART;SM00304:This domain is known as the HAMP domain for histidine kinases,adenylyl cyclases, methyl binding proteins and phosphatases. It is found in bacterial sensor and chemotaxis proteins and in eukaryotic histidine kinases. The bacterial proteins are usually integral membrane proteins and part of a two-component signal transduction pathway. Has IPR000160_GGDEF(SMART;SM00267);This domain is found linked to a wide range of non-homologous domains in [...]
    
   0.894
azo1476
Conserved hypothetical membrane protein.
    
   0.894
azo1879
Conserved hypothetical signaling protein. Homology to Daro03001110 of Dechloromonas aromatica of 33% (gi|46141071|ref|ZP_00203851.1|(NBCI ENTREZ)). InterPro: IPR003660 HAMP. IPR000160 GGDEF. Pfam: PF00563 EAL domain. PF00672 HAMP. PF00990 GGDEF domain. TIGRFAM:TIGR00254 putative diguanylate cyclase (GGDEF) domain. Signal P reporting signal peptide. TMHMM reporting 3 transmembrane helices; Conserved hypothetical protein.
    
   0.894
azo2712
GGDEF/PAS/PAC-domain containing protein,; Conserved hypothetical protein.
    
   0.894
amtE
Probable ammonia permease with sensory box/GGDEF domains; Putative ammonium transporter with sensory/GGDEF boxes. TREMBL:Q88M14: 50% identity; 65% similarity; TREMBL:Q7UK31: 46% identity; 58% siilarity InterPro:IPR001633; EAL. IPR000160; GGDEF. IPR001610; PAC. IPR000014; PAS_domain. IPR001905; Ammonium_transpt. IPR003594; ATPbind_ATPase Pfam: PF00563; EAL; PF00990; GGDEF; PF00785; PAC; PF00989; PAS; PF00909; Ammonium_transp SMART SM00267; DUF1; SM00052; DUF2; SM00086; PAC; SM00091; PAS amt: ammonium transporter Nonsecretory protein with signal peptide (SignalP predicted). Presence of 1 [...]
    
   0.894
azo3061
GGDEF/EAL/PAS/PAC/GAF-domain containing protein.
    
   0.894
azo3527
GGDEF/EAL-domain containing protein.
    
   0.894
azo3665
Conserved hypothetical signaling protein. Homology to IL2267 of Idiomarina loihiensis of 35% (gnl|keqq|ilo:IL2267(KEGG)). InterPro: IPR001633 EAL. IPR000160 GGDEF. Pfam: PF00563 EAL. PF00990 GGDEF. SMART: SM00267 DUF1. SM00052 DUF2. TIGRFAM:TIGR00254 GGDEF. Signaling protein ykoW. Probable signaling protein whose physiological role is not yet known. no signal peptide. No TMHs; Conserved hypothetical protein.
    
   0.894
azo3849
GGDEF/EAL/PAS/PAC-domain containing protein.
    
   0.894
holB
DNA polymerase III delta subunit. DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity (By similarity). TIGRFAM: holB: DNA polymerase III delta prime; High confidence in function and specificity.
     
 0.842
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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