STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hipO2Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7WFU4: 48% identity, 58% similarity InterPro:IPR002933; Peptidase_M20. IPR010168; Pept_M20D_amidh. Pfam: PF01546; Peptidase_M20; 1. TIGRFAMs TIGR01891; amidohydrolases No signal peptide present No transmembrane helices present mreB: cell shape determining protein M; High confidence in function and specificity. (389 aa)    
Predicted Functional Partners:
azo1606
Putative inner membrane transport permease; Similar to TREMBL:Q7WGZ1 (41% identity); TREMBL:Q7W9R7 (41% identity); TREMBL:Q8XXM2 (37% identity). Pfam (DUF214): Predicted permease. TMHMM reporting 10 transmembrane helices; Specificity unclear.
  
    0.768
gltB
Ferredoxin-dependent glutamate synthase,; Specificity unclear.
    
  0.715
dapD
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. Homology to dapD of E. coli of 74% (sprot|DAPD_ECOLI). Involved in biosynthesis of diaminopimelate and lysine from aspartate semialdehyde. Catalytic activity: succinyl-coa + (r)-2,3,4,5-tetrahydropyridine- 2,6-dicarboxylate + h(2)o = coa + (r)-2-(succinylamino)-6- oxoheptanedioate. InterPro: Bacterial transferase hexapeptide repeat (IPR001451) no signal peptide no TMH; High confidence in function and specificity.
 
  
 0.559
azo1603
Conserved hypothetical protein,52% Identity to TrEMBL;Q9HUN7. Has PF04169;Domain of unknown function (DUF404);(IPR007297)This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF407 (IPR007302). Has PF04174;Domain of unknown function (DUF407);This is a protein of unknown function. It sometimes occurs in combination with two domains of unknown function DUF403 (IPR007296) and DUF404 (IPR007297). Has PF04168;Bacterial domain of unknown function (DUF403);This is a protein of unknown function. It sometimes occur [...]
    
  0.510
dapF
DapF protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.485
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
    
  0.477
azo1604
Conserved hypothetical protein; Transglutaminase-like superfamily domain protein;67% identity (79% similarity) to TrEMBL;Q87VL0. TrEMBL;Q6N3E0(57% identity). Has SMART;SM00460,TGc;Transglutaminase/protease-like homologues: (IPR002931):Transglutaminases are enzymes that establish covalent links between proteins. A subset of transglutaminase homologues appear to catalyse the reverse reaction, the hydrolysis of peptide bonds. Proteins with this domain are both extracellular and intracellular, and it is likely that the eukaryotic intracellular proteins are involved in signalling events. NO [...]
       0.455
ggt
Ggt protein; Gamma-glutamyltranspeptidase catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GGT plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione and drug and xenobiotic detoxification. Similar to trembl|Q88H30 (43%)and to trembl|Q8UJH0 (36%). TIGRfam (TIGR00066): Gamma-glutamyltranspeptidase Pfam (PF01019): Gamma-glutamyltranspeptidase SignalP reporting Signal peptide; Specificity unclear.
    
  0.411
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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