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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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[Homology]
Score
azo1606Putative inner membrane transport permease; Similar to TREMBL:Q7WGZ1 (41% identity); TREMBL:Q7W9R7 (41% identity); TREMBL:Q8XXM2 (37% identity). Pfam (DUF214): Predicted permease. TMHMM reporting 10 transmembrane helices; Specificity unclear. (830 aa)    
Predicted Functional Partners:
tesA1
Probable acyl-CoA thioesterase. Homology to tesA of E. coli of 42% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase with GDSL-like motif signal peptide no TMH; Family membership.
 
 
   0.903
azo1667
Putative ABC transporter ATP-binding protein; Similar to TREMBL:Q82UM8 (55% identity); TREMBL:Q8XYP0 (59% identity); TREMBL:Q7W685 (59% identity). Pfam (PF00005): ABC transporter; Specificity unclear.
 
 
 
 0.884
tesA2
Putative acyl-CoA thioesterase. Homology to tesA of E. coli of 32% (sprot|TESA_ECOLI) Hydrolyzes long chain acyl thioesters (c12-c18): 2-lysophosphatidylcholine + h(2)o = glycerophosphocholine + a fatty acid anion. InterPro: GDSL lipolytic enzyme (IPR001087) Pfam: Lipase/Acylhydrolase GDSL-like motif signal peptide no TMH; Family membership.
 
 
   0.876
macB
ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.866
azo1880
Conserved hypothetical secreted protein. TREMBL:O86370 (36% identity); TREMBL:Q7U0W8 (36% identity). No domains predicted. SignalP reporting signal peptide. No TMHs; Conserved hypothetical protein.
 
  
 0.779
hipO2
Hippurate hydrolase (EC 3.5.1.32) (Benzoylglycine amidohydrolase) (Hippuricase). TREMBL:Q7WFU4: 48% identity, 58% similarity InterPro:IPR002933; Peptidase_M20. IPR010168; Pept_M20D_amidh. Pfam: PF01546; Peptidase_M20; 1. TIGRFAMs TIGR01891; amidohydrolases No signal peptide present No transmembrane helices present mreB: cell shape determining protein M; High confidence in function and specificity.
  
    0.769
azo0832
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8DJ46 (29% identity); TREMBL:Q8YZK5 (29% identity). InterPro (IPR003838): Protein of unknown function DUF214. Pfam (DUF214): Predicted permease. TMHMM reporting four transmembrane helices. TC (3.A.1.122.): The Macr [...]
  
 
  0.732
azo0833
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q8YZK5 (28% identity); TREMBL:Q8DJ46 (29% identity). Pfam (DUF214): Predicted permease. TMHMM reporting five transmembrane helices. TC (3.A.1.122.): The Macrolide Exporter (MacB) Family; Specificity unclear.
  
 
  0.732
azo0807
Conserved hypothetical membrane protein Similar to TREMBL:Q7P0W7 (65% identity); TREMBL:Q82SF6 (65% identity); TREMBL:Q7VSZ9 (57% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
     
 0.618
azo1274
Putative ABC transporter permease protein; TREMBL:Q88RI7 (56% identity); TREMBL:Q8PGP6 (42% identity). Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting six transmembrane helices; Specificity unclear.
     
 0.618
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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