STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadBL-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (529 aa)    
Predicted Functional Partners:
nadA
Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase). TIGRFAM: nadC: nicotinate-nucleotide pyrophosphorylase; High confidence in function and specificity; Belongs to the NadC/ModD family.
  
 0.996
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.940
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
    
 0.940
azo0436
L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase); Family membership.
   
 
 0.936
modD
Putative molybdenum transport protein; Putative pyrophosphorylase modD (EC 2.4.2.-). InterPro: Quinolinate phosphoribosyl transferase; Specificity unclear; Belongs to the NadC/ModD family.
 
  
 0.932
pyrB
Aspartate carbamoyltransferase (Aspartate transcarbamylase) (Carbamylaspartotranskinase) (ATCase); High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.930
ansB2
Periplasmic L-asparaginase II; L-asparaginase precursor (EC 3.5.1.1) (L-asparagine amidohydrolase) (L-ASNase); High confidence in function and specificity; Belongs to the asparaginase 1 family.
   
 
 0.926
lysC
Aspartate kinase (AK) catalyzes the phosphorylation of aspartate. The product of this reaction can then be used in the biosynthesis of lysine or in the pathway leading to homoserine, which participates in the biosynthesis of threonine, isoleucine and methionine. Similar to trembl|Q8RU02 (80%) and to pir|C83531 (74%). Pfam (PF00696): Amino acid kinase family Pfam (PF01842): two ACT domain; High confidence in function and specificity; Belongs to the aspartokinase family.
    
 0.919
gltA
Probable citrate synthase. Homology to gltA of s. meliloti of 69% (sprot|CISY_RHIME). Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs' cycle: Citrate + CoA = acetyl-CoA + H2 O + oxaloacetate InterPro: Citrate synthase (IPR002020) Pfam: Citrate synthase no signal peptide no TMHs; High confidence in function and specificity.
     
 0.917
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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