STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rseBPutative sigma factor regulatory protein,; High confidence in function and specificity. (323 aa)    
Predicted Functional Partners:
rseA
Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity.
 
 0.999
rseC
Putative sigma-E factor regulatory protein RseC,; High confidence in function and specificity.
  
  
 0.983
algU
RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
 
 0.963
azo0559
Hypothetical sigma-E factor regulatory protein,best similarity to SWISSPROT: sprot|Y850_HAEIN (Haemophilus influenzae, hypothetical protein hi0850) / sprot|RSEC_ECOLI (23% Escherichia coli, sigma-e factor regulatory protein RseC). TMHMM reporting 2 transmembrane helices.
  
  
 0.874
azo1635
Thioredoxin-disulfide reductase; Conserved hypothetical thioredoxin. Homology to a putative thioredoxin of N. menigitidis (NMA0966) of 50%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. no signal peptide no TMHs; Function unclear.
       0.799
mucD2
Probable serine protease MucD. Homology to mucD of P. aruginosa of 47% (trembl|Q57155) InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (also known as DHR or GLGF) (IPR001478); Chymotrypsin serin protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs ahpD_dom: alkylhydroperoxidase AhpD fam; High confidence in function and specificity; Belongs to the peptidase S1C family.
  
  
 0.789
rpoS
Putative RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.
     
 0.737
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.736
sigZ
Putative RNA polymerase sigma factor sigZ. The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released. Similar to SWISSPROT: sprot|SIGZ_BACSU (23% Bacillus subtilis, RNA polymerase sigma factor SigZ) / sprot|RPSH_PSEAE (28% Pseudomonas aeruginosa, RNA polymerase sigma-h factor (sigma-30), AlgU or AlgT) InterPro: IPR000838 Sigma70_ECF. Pfam: PF07638 ECF sigma factor; High confidence in function and specificity.
 
 0.704
rpoE
Probable RNA polymerase sigma-E factor (sigma-24),; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
 0.671
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (16%) [HD]