STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1635Thioredoxin-disulfide reductase; Conserved hypothetical thioredoxin. Homology to a putative thioredoxin of N. menigitidis (NMA0966) of 50%. Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. no signal peptide no TMHs; Function unclear. (85 aa)    
Predicted Functional Partners:
azo1411
Conserved hypothetical ribonucleoside reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.942
msrA
Putative peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.821
rseA
Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity.
       0.800
rseB
Putative sigma factor regulatory protein,; High confidence in function and specificity.
       0.800
rseC
Putative sigma-E factor regulatory protein RseC,; High confidence in function and specificity.
     
 0.800
mucD2
Probable serine protease MucD. Homology to mucD of P. aruginosa of 47% (trembl|Q57155) InterPro: Serine proteases trypsin family (IPR001254); PDZ domain (also known as DHR or GLGF) (IPR001478); Chymotrypsin serin protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs ahpD_dom: alkylhydroperoxidase AhpD fam; High confidence in function and specificity; Belongs to the peptidase S1C family.
   
   0.790
algU
RNA polymerase sigma factor, Myxococcus xanthus carQ; Alcaligenes eutrophus plasmid pMOL28-encoded cnrH; Escherichia coli fecI; Pseudomonas syringae hrpL; rpoE from Escherichia coli, Salmonella typhimurium and Haemophilus influenzae; Streptomyces coelicolor sigE; and Bacillus subtilis sigma factors sigV, sigX, sigY and sigZ; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.777
metH
Probable methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.688
ribAB
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.655
priB
Putative primosomal replication proteinN; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.632
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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