STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1638Putative exported protein, 39% identity (54% similarity)to TrEMBL;Q7VUI5 TrEMBL;Q7WNJ8. Has PF03401;Bordetella uptake gene (bug) product;(IPR005064)These probable extra-cytoplasmic solute receptors are strongly overrepresented in several beta-proteobacteria. SIgnal Peptide Present. No TMH reported present; Specificity unclear. (321 aa)    
Predicted Functional Partners:
azo2387
Conserved hypothetical membrane protein. Homology to an orf of R. palustris of 63% (tremblnew|CAE27761(SRS)). Has PF01970, Integral membrane protein DUF112;IPR002823:Members of this prokaryotic family have no known function. no signal peptide. 10 TMHs; Conserved hypothetical protein.
  
 0.975
azo2386
Conserved hypothetical membrane protein. Homology to BB4221 of Bordetella bronchiseptica of 32% (trembl|Q7WFQ0). Has PF07331, Protein of unknown function (DUF1468);IPR009936;This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein.
 
  
 0.956
azo1637
Hypothetical membrane protein. No homology to the data bank. No domains predicted. No signal peptide 3 TMHs.
       0.668
azo1917
Conserved hypothetical membrane protein. Homology to so0455 of S. oneidensis of 65% (trembl|Q8EJK8). Tigrfam: dctM: TRAP dicarboxylate transporter-DctM subunit. Pfam: TRAP C4-dicarboxylate transport (Dct) system permease DctM subunit. This domain represents a conserved region located towards the N terminus of the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. no signal peptide. 17 TMHs; Conserved hypothetical protein.
  
     0.533
fsr
A gene conferring resistance to fosmidomycin (Fs) encode a putative polypeptide of 406 amino acids (aa) with a molecular weight of 43303 in E.coli. 23% similarity to B. japonicum fsr. A comparison between the aa sequence of Fsr and sequences in a protein database revealed 18% homology to the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. Hydropathy analysis of the Fsr protein revealed twelve putative transmembrane segments. Fsr does not have any direct effect on the biosynthesis of isoprenoid in E. coli, and that the mechanism for FsR involv [...]
  
     0.477
azo1636
HTH-type transcriptional regulator,; Family membership; Belongs to the LysR transcriptional regulatory family.
       0.471
azo1918
Conserved hypothetical secreted protein. Homology to pp3954 pf P. putida of 64% (trembl|Q88FX3). no domains predicted. singal peptide. TMH in signal peptide; Conserved hypothetical protein.
  
   
 0.460
dctP1
Putative ABC transporter periplasmic binding protein, DctP: TRAP dicarboxylate transporter.Binds C4-dicarboxylates; part of the binding-protein- dependent transport system for uptake of c4-dicarboxylates. 28% TRAP_transptDctP. Pfam:PF03480; SBP_bac_7; 1. TIGRFAMs:TIGR00787; dctP; 1. Signal peptide:present. TMhelix:1; Specificity unclear.
  
     0.444
dctM1
TRAP-type C4-dicarboxylate transport system, large permease component, DctM.The Dct locus encodes a high-affinity transport system for the C4-dicarboxylates malate,succinate, and fumarate. 34% DctM.IPR000252; DedA.IPR004681; TRAP_transptDctM. Pfam:PF06808; DctM; 1.PF00597; DedA; 1. TIGRFAMs:TIGR00786; dctM; 1. Signal peptide: present. TMhelix:11; Specificity unclear.
  
     0.401
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.