STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1660Conserved hypothetical protein; Possible aldose 1-epimerase.Aldose 1-epimerase (mutarotase), responsible for the anomeric interconversion of D-glucose and other aldoses between their alpha- and beta-forms. InterPro:IPR008183; Ald1_epimerase. Pfam:PF01263; Aldose_epim; 1; Belongs to the glucose-6-phosphate 1-epimerase family. (283 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase 1(EC 5.3.1.9) (GPI 1)(Phosphoglucose isomerase 1)(PGI 1)(Phosphohexose isomerase 1) (PHI 1). Enzyme involved in glycolysis and in gluconeogenesis.Catalytic activity: d-glucose 6-phosphate = d-fructose 6- phosphate.Belongs to the gpi family. 39% G6P_Isomerase. Pfam:PF00342; PGI; 1; High confidence in function and specificity.
  
 
 0.939
pgm
Phosphomannomutase/phosphoglucomutase (PMM / PGM). The phosphomannomutase activity produces a precursor for alginate polymerization. This enzyme participates in both the breakdown and synthesis of glucose.Catalytic activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 58% PG/PMM_mutase.IPR005844; PG_PMM_ABAI.IPR005845; PG_PMM_ABAII.IPR005846; PG_PMM_ABAIII.IPR005843; PG_PMM_C. Pfam:PF02878; PGM_PMM_I; 1.PF02879; PGM_PMM_II; 1.PF02880; PGM_PMM_III. PF00408; PGM_PMM_IV; 1; High confidence in function and specificity.
    
 0.933
tkt
Putative transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
  
 0.933
azo1661
Conserved hypothetical protein. Homology to cv3676 of C. violaceum of 47% (trembl|Q7NRV4). InterPro: DUF184 (IPR003781). Pfam: CoA binding domain; Acetyltransferase (GNAT) family. No signal peptide. No TMHs.
       0.785
azo3329
Putative 3',5'-cyclic-nucleotide phosphodiesterase; Probable 35-cyclic-nucleotide phosphodiesterase precursor (EC 3.1.4.17) (PDEase) (3:5-CNP). TREMBL:Q8ZD92:28% identity, 47% similarity InterPro; IPR001279; Blactmase-like. IPR000396; Pdiesterase2. Pfam: PF00753; Lactamase_B No transmembrane helices TIGR00010: deoxyribonuclease TatD fami; Function unclear.
  
 
   0.781
glk1
Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 34% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1; High confidence in function and specificity; Belongs to the bacterial glucokinase family.
    
  0.663
glk2
Glucokinase (EC 2.7.1.2) (Glucose kinase). Catalytic activity: ATP + d-glucose = ADP+ d-glucose 6-phosphate. 24% Glucokinase. Pfam:PF02685; Glucokinase; 1. TIGRFAMs:TIGR00749; glk; 1; High confidence in function and specificity; Belongs to the bacterial glucokinase family.
    
  0.663
azo1337
Conserved hypothetical peptidoglycan binding protein. Homology to bb3579 of b. bronchiseptica of 69% (trembl|Q7WGL0) InterPro: Putative peptidoglycan binding domain 1 (IPR002477) Pfam: Putative peptidoglycan binding domain This domain is composed of three alpha helices. This domain is found at the N or C terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. signal peptide no TMHs; Family membership.
 
      0.630
ilvD
Dihydroxy-acid dehydratase catalyzes the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisovaleric acid. Similar to sprot|ILVD_PSEAE (74%) and sprot|ILVD_ECOL6 (72%). TIGRfam (TIGR00110): Dihydroxy-acid dehydratase Pfam (PF00920): Dihydroxy-acid and 6-phosphogluconate dehydratase; High confidence in function and specificity; Belongs to the IlvD/Edd family.
      0.537
tex
Transcription accessory protein (S1-domain containing RNA binding protein),; High confidence in function and specificity.
       0.508
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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