STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo1680Hypothetical UPF0103 protein ST2062. This gene is conserved in several species ranging from Caenorhabditis elegans and yeast to plants and micro-organisms although no function has yet been ascribed to the other proteins in this family. TREMBL:Q843N3: 38% identity,52% similarity InterPro:IPR002733; DUF51. IPR002737; DUF52. Pfam: PF01871; AMMECR1; 1. PF01875; UPF0103 Signal peptide present No transmembrane helices holB: DNA polymerase III delta prime sub; Function unclear. (274 aa)    
Predicted Functional Partners:
azo1679
Hypothetical protein, 38% identity to SwissProt;O26945 Has PF01871;AMMECR1;(IPR002733, DUF 51)This family consists of several AMMECR1 as well as several uncharacterised proteins. The contiguous gene deletion syndrome AMME is characterised by Alport syndrome, midface hypoplasia, mental retardation and elliptocytosis and is caused by a deletion in Xq22.3,comprising several genes including COL4A5, FACL4 and AMMECR1. This family contains sequences from several eukaryotic species as well as archaebacteria and it has been suggested that the AMMECR1 protein may have a basic cellular function, [...]
    0.997
pflA
Conserved hypothetical pyruvat formate-lyase activiating enzyme. Homology to pflA of M. tuberculosis of 64% (trembl|P95188). no domains predicted no signal peptide no TMHs; Family membership.
     0.928
azo1681
Conserved hypothetical membrane protein. TrEMBL; Q82Y76(48% identity). TMHMM2 reporting 14 TMH's present. Signal Peptide not present. Has PF02308;MgtC family;(IPR003416 MgtCSapB_transpt)The MgtC protein is found in an operon with the Mg2+ transporter protein MgtB. The function of MgtC and its homologues is not known, but it is thought that MgtC may act as an accessory protein for MgtB, thus mediating magnesium influx into the cytosol. Also included in this family are the Bacillus subtilis SapB protein and several hypothetical proteins. Has PF04093 rod shape-determining protein MreD;IPR [...]
       0.661
azo1678
Putative cyclic nucleotide-binding protein,; Specificity unclear.
       0.645
cowN
Conserved hypothetical protein; Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.
       0.513
ispD
Probable 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
       0.506
ispF
Probable 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
       0.503
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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