STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1694Conserved hypothetical protein. Homology to ebA6519 of Azoarcus sp. EbN1 of 44% (gnl|keqq|eba:ebA6519(KEGG)). no domains predicted. signal peptide present. no TMHs. (216 aa)    
Predicted Functional Partners:
azo1693
Conserved hypothetical secreted protein. Homology to bb0165 of B. bronchiseptica of 31% (TREMBL:Q7WR07). Pfam: mce related protein This family of proteins contains the mce (mycobacterial cell entry) proteins from Mycobacterium tuberculosis. The archetype (Rv0169), was isolated as being necessary for colonisation of, and survival within, the macrophage. This family contains proteins of unknown function from other bacteria. Signal peptide. no TMHs; Conserved hypothetical protein.
 
     0.945
azo1691
Conserved hypothetical membrane protein. Similar to TREMBL:Q8Y2M2 (43% identity). InterPro (IPR003453): Domain of unknown function DUF140. Pfam (PF02405): Domain of unknown function DUF140. TIGRFAM (TIGR00056): Conserved hypothetical protein. TMHMM reporting five transmembrane helices.
 
     0.929
azo1692
ATP-binding cassette (ABC) transporters form a large family of proteins responsible for translocation of a variety of compounds across biological membranes. They are composed of two transmembrane domains responsible for binding and transport and two nucleotide-binding domains responsible for coupling the energy of ATP hydrolysis to conformational changes in the TMDs, TREMBL:Q7W0L5 (51% identity); TREMBL:Q9A5X8 (46% identity). InterPro (IPR001687): ATP/GTP-binding site motif A (P-loop). InterPro (IPR003593): AAA ATPase. InterPro (IPR003439): ABC transporter. Pfam (PF00005): ABC transpor [...]
 
     0.869
azo3728
Probable lipoprotein, 58% similarity to TrEMBL:Q8XWT8 PROBABLE LIPOPROTEIN [RS01163] [Ralstonia solanacearum (Pseudomonas solanacearum)]. Has PF04355:IPR007450:SmpA / OmlA family;Lipoprotein Bacterial outer membrane lipoprotein, possibly involved in in maintaining the structural integrity of the cell envelope [1]. Lipid attachment site is a conserved N terminal cysteine residue. Sometimes found adjacent to the OmpA domain (OmpA). Signal peptide present. NO TMH reported present; Family membership.
  
    0.646
azo1695
Putative AMP-binding protein; Similar to TREMBL:Q9HWI3 (58% identity); TREMBL:Q89LN0 (56% identity); TREMBL:Q986M2 (56% identity). InterPro (IPR000873): AMP-dependent synthetase and ligase. Pfam (PF00501): AMP-binding enzyme; Function unclear.
       0.618
ppx
Putative exopolyphosphatase; 45% Ppx_GppA. Pfam:PF02541; Ppx-GppA; 1; High confidence in function and specificity.
       0.544
azo2194
Conserved hypothetical membrane protein. Homology to rs04519 of R. solanacearum of 33% (trembl|Q8Y0Z7(SRS)). no domains predicted. no signal peptide. 1 TMHs; Conserved hypothetical protein.
  
    0.536
azo2154
Conserved hypothetical secreted protein. 33% similarity to TrEMBL Q8XQF8 PROBABLE SIGNAL PEPTIDE PROTEIN [RS05314] [Ralstonia solanacearum (Pseudomonas solanacearum)]. No domains predicted. Signal P reporting signal peptide present. No TMH reported being present; Conserved hypothetical protein.
  
     0.520
azo3727
Conserved hypothetical secreted protein. Homology to ebA3180 of Azoarcus sp. EbN1 of 57% (gi|56477224|ref|YP_158813.1|(NBCI ENTREZ)). No domains predicted Signal Peptide present. No TMH reported present; Conserved hypothetical protein.
  
    0.507
azo3121
Putative endonuclease,42% Identity to TrEMBL;Q8XWM2, 33% Identity to TrEMBL;Q8VMF9. Has Signal peptide. Has PLDc, Phospholipase D. Active site motifs; The PLD superfamily includes enzymes involved in signal transduction, lipid biosynthesis, endonucleases and open reading frames in pathogenic viruses and bacteria. PLD hydrolyzes the terminal phosphodiester bond of phospholipids to phosphatidic acid and a hydrophilic constituent. Phosphatidic acid is a compound that is heavily involved in signal transduction. The common features of the family members are that they can bind to a phosphodi [...]
  
     0.470
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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