Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
paaF2Putative enoyl-CoA hydratase. Homology to paaF of E. coli of 36% (sprot|PAAF_ECOLI(SRS)) FUNCTION: Could possibly oxidizes fatty acids using specific components (By similarity). CATALYTIC ACTIVITY: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Pfam: Enoyl-CoA hydratase/isomerase family no signal peptide no TMHs; Family membership. (266 aa)    
Predicted Functional Partners:
fadA2
Probable 3-ketoacyl-CoA thiolase; Activity:- acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name:- SWISSPROT:THIK_ECOLI Prim. accession # P21151 InterPro:- IPR002155; Thiolase. Pfam:-PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 177/400 (44%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.880
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
    
 0.838
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
    
 0.824
rpsN
30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.
  
 
  0.810
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
    
 0.801
hbdA
Probable 3-hydroxybutyryl-CoA dehydrogenase; Activity:- (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+ Entry name :- TREMBL:Q89GX2 Prim. accession # Q89GX2 Identities = 177/280 (63%) InterPro:- IPR006108; 3HCDH_C. IPR006176; 3HCDH_N. IPR008927; 6DGDH_C_like. IPR000205; NAD_BS. Pfam :-PF00725; 3HCDH; 1. PF02737; 3HCDH_N; 1. Prediction: Signal peptide Signal peptide probability: 0.873 Number of predicted TMHs: 0; Family membership.
 0.800
rpsF
RpsF protein; Binds together with S18 to 16S ribosomal RNA.
    
 0.799
rpsB
30S ribosomal protein S2. InterPro: Ribosomal protein S2; High confidence in function and specificity; Belongs to the universal ribosomal protein uS2 family.
    
 0.799
rpsI
30S ribosomal protein S9; High confidence in function and specificity; Belongs to the universal ribosomal protein uS9 family.
    
  0.799
rpsP
30S ribosomal protein S16; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bS16 family.
    
  0.799
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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