close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1707Conserved hypothetical globin-like protein. Homology to bd2638 of B. bacteriovorus of 57% (tremblnew|CAE80431). Globins are heme-containing proteins involved in binding and/or transporting oxygen. This family of heme binding proteins are found mainly in bacteria. However they can also be found in some protozoa and plants as well. InterPro: Protozoan/cyanobacterial globins (IPR001486) Pfam: Bacterial-like globin. no signal peptide. no TMHs; Family membership. (137 aa)    
Predicted Functional Partners:
cbf2
Cell binding factor 2 precursor (Major antigen peb4A). Homology to cbf2 of C. jejuni of 34% (sprot|CBF2_CAMJE). Belongs to the ppic/parvulin rotamase family InterPro: PpiC-type peptidyl-prolyl cis-trans isomerase (IPR000297) Pfam: PPIC-type PPIASE domain signal peptide no TMH; Family membership.
       0.636
azo1704
Putative BolA-like protein; Region start changed from 1873054 to 1872976 (-78 bases); Belongs to the BolA/IbaG family.
       0.636
yciI
Putative cytoplasmic protein,61% Identity to SwissProt;P31070, TrEMBL;Q7CQF5. Has Signal peptide. Has PF03795, YCII-related domain;IPR005545; The majority of proteins in this family consist of a single copy of this domain, though it is also found as a repeat (Q9AJZ7). A strongly conserved histidine and a aspartate suggest that the domain has an enzymatic function.
       0.636
ispZ
Putative intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
       0.636
ompR1
Transcriptional regulatory protein ompR,Trans_reg_C. IPR001789 Response_reg. Pfam: PF00486; trans_reg_C. PF00072 response_reg. SMART: SM00448 REC. THE N-TERMINUS OF THIS PROTEIN IS REQUIRED FOR THE TRANSCRIPTIONAL EXPRESSION OF BOTH MAJOR OUTER MEMBRANE PROTEIN GENES OMPF AND OMPC; ITS CARBOXYL-TERMINAL MOIETY MEDIATES THE MULTIMERIZATION OF THE OMPR PROTEIN. AS A MULTIMER IT TURNS ON THE EXPRESSION OF THE OMPC GENE; AS A MONOMER IT TURNS ON THE EXPRESSION OF THE OMPF GENE; High confidence in function and specificity.
    
  0.559
envZ1
Probable osmolarity sensor protein EnvZ,; Specificity unclear.
       0.522
pilL
Putative pilus biogenese protein, ATPbind_ATPase. IPR004358; Bact_sens_pr_C. IPR002545; CheW. IPR004105; H-kinase_dim. IPR005467; His_kinase. IPR008207; Hpt. IPR008208; Hpt_N. IPR001789; Response_reg. Pfam: PF01584; CheW. PF02895; H-kinase_dim. PF02518; HATPase_c. PF01627; Hpt. PF00072; Response_reg. SMART: SM00260; CheW. SM00387; HATPase_c. SM00073; HPT. SM00448; REC. HTH reporting nucleic acid binding motif; Function unclear.
    
  0.522
azo3381
Hypothetical signaling protein.
    
  0.515
cheV1
Probable chemotaxis protein, CheW. IPR001789; Response_reg. Pfam: PF01584; CheW. PF00072; Response_reg. SMART: SM00260; CheW. SM00448; REC. Chemotaxis protein cheV. CHEMOTAXIS INVOLVES BOTH A PHOSPHORYLATION-DEPENDENT EXCITATION AND A METHYLATION-DEPENDENT ADAPTATION. CHEV AND CHEW FUNCTION TOGETHER TO COUPLE CHEA ACTIVATION TO METHYL-ACCEPTING CHEMOTAXIS PROTEIN RECEPTOR STATUS AND POSSIBLE CHEA-DEPENDENT PHOSPHORYLATION OF CHEV CONTRIBUTES TO ADAPTATION; High confidence in function and specificity.
    
  0.479
azo1490
Conserved hypothetical signaling protein. Homology to ebA6472 Azoarcus sp. EbN1 of 36% (gnl|keqq|eba:ebA6472(KEGG)). InterPro: IPR000160 GGDEF. IPR000014 PAS. IPR000700 PAS-assoc_C. IPR001789 Response_reg. Pfam: PF00990 GGDEF domain. PF00989 PAS domain. PF00785 PAC motif. PF01590 GAF domain. PF00563 EAL domain. PF00072 Response_reg. TIGRFAM:TIGR00229 PAS domain S-box. TIGR00254 putative diguanylate cyclase (GGDEF) domain. No signal peptide. No TMHs; Conserved hypothetical protein.
    
  0.459
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.