STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbcRTrans-acting transcriptional regulator of RuBisCO genes expression Putative HTH-type transcriptional regulator Contains 1 HTH lysR-type DNA-binding domain,belonds to the LysR family InterPro: Bacterial regulatory protein LysR family ModE_repress: ModE molybdate transport 32% HTH_LysR. IPR005119; LysR_subst. IPR009058; Wing_hlx_DNA_bnd. PF00126; HTH_1; 1. PF03466; LysR_substrate; 1; High confidence in function and specificity. (306 aa)    
Predicted Functional Partners:
radA
Probable DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.801
azo1636
HTH-type transcriptional regulator,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.676
azo2600
Transcriptional regulator, LysR family This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression. 37% 1 helixturnhelix PF03466 LysR_substrate; 1. HTH reporting nucleic acid binding motif; Specificity unclear.
  
     0.660
ltrA
Putative transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.575
azo0020
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.574
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.573
bdhR
Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.571
lysR
Putative transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.571
azo1015
Probable transcriptional regulator, LysR family,; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.565
azo1714
Permease,member of the Major Facilitator Superfamiliy (MFS)transporters. MFS are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Homolog to the hypothetical protein ygeD, a putative resistence protein from Y. pestis(by similarity). 2A0121: H+ Antiporter protein; High confidence in function and specificity.
       0.556
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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