STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1752Conserved hypothetical secreted protein: Homology to ne0129 of N. europaea of 43% (trembl|Q82XW6). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. no TMHs; Conserved hypothetical protein. (107 aa)    
Predicted Functional Partners:
azo1750
Hypothetical membrane protein. No homology of the entire protein to the data bank. Has DUF1328(Protein of Unknown family) domain. PF07043;IPR009760; This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. no signal peptide. 3 TMHs.
  
    0.842
cls2
Function:- Cardiolipin synthetase (CL synthase),cls. Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Entry name :-SWISSPROT:CLS_ECOLI Prim. accession # P31071 InterPro:IPR001736; PLD. Identities = 114/379 (30%) Pfam:PF00614; PLDc; 2. TMhelix=1 Signal peptide probability: 1.0; Family membership.
  
    0.777
azo3770
Conserved hypothetical protein, 43% identity (60% similarity) to TrEMBL; Q8ZML9. TrEMBL;Q8X937(44% identity to Escherichia coli) Has PF04972, Putative phospholipid-binding domain;IPR007055, TAD; This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. Has SMART;SM00257,LysM, Lysin motif:IPR002482; This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation. This domain [...]
  
  
 0.695
azo1765
Conserved hypothetical membrane protein. Homology to Atu4467 of Agrobacterium tumefaciens of 58% (trembl|Q8U7I2). Has PF07043, Protein of unknown function (DUF1328);IPR009760;This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. signal peptide. 1 TMHs; Conserved hypothetical protein.
  
    0.676
azo1754
Conserved hypothetical membrane protein. Homology Avin02003871 of Azotobacter vinelandii of 47% (gi|53610588|ref|ZP_00089122.2|(NBCI ENTREZ)). Has PF03653, Uncharacterised protein family (UPF0093). Interpro: IPR005265; Cons_hypoth701; It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein.
       0.618
azo1749
Conserved hypothetical membrane protein. Homology to r02018 of S. meliloti of 72% (trembl|Q92K67(SRS). no damains predicted .signal peptide. 1 TMH; Conserved hypothetical protein.
 
     0.615
azo3667
Conserved hypothetical membrane protein. Homology to RS05100 of Ralstonia solanacearum of 50% (trembl|Q8Y1D7(SRS)). Has PF05957, Bacterial protein of unknown function (DUF883);IPR010279; This family consists of several hypothetical bacterial proteins of unknown function. no signal peptide. 1 TMH; Conserved hypothetical protein.
 
    0.565
azo2990
Putative isochorismatase; Similar to TREMBL:Q88PY7 (90% identity); SWISSPROT:P21367 (87% identity); TREMBL:Q7W0U0 (85% identity). InterPro (IPR000868): Isochorismatase hydrolase. Pfam (PF00857): Isochorismatase family; Specificity unclear.
  
    0.550
azo1751
Conserved hypothetical secreted protein. Homology to ebA6968 of Azoarcus sp. EbN1 of 38% (gnl|keqq|eba:ebA6968(KEGG)). Pfam: Putative phospholipid-binding domain This domain is found in a family of osmotic shock protection proteins (e.g. P27291). It is also found in some Secretins and a group of potential haemolysins. Its likely function is attachment to phospholipid membranes. No TMHs. Signal peptide present; Conserved hypothetical protein.
       0.538
azo3768
Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.514
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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