STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1754Conserved hypothetical membrane protein. Homology Avin02003871 of Azotobacter vinelandii of 47% (gi|53610588|ref|ZP_00089122.2|(NBCI ENTREZ)). Has PF03653, Uncharacterised protein family (UPF0093). Interpro: IPR005265; Cons_hypoth701; It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. Signal peptide. 3 TMHs; Conserved hypothetical protein. (139 aa)    
Predicted Functional Partners:
azo1755
Conserved hypothetical membrane protein. Homology ebA159 of Azoarcus sp. EbN1 of 52% (gnl|keqq|eba:ebA159(KEGG)). No domains predicted. no signal peptide. 4 TMHs; Conserved hypothetical protein.
  
     0.623
azo1752
Conserved hypothetical secreted protein: Homology to ne0129 of N. europaea of 43% (trembl|Q82XW6). Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. signal peptide. no TMHs; Conserved hypothetical protein.
       0.618
cls2
Function:- Cardiolipin synthetase (CL synthase),cls. Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. Entry name :-SWISSPROT:CLS_ECOLI Prim. accession # P31071 InterPro:IPR001736; PLD. Identities = 114/379 (30%) Pfam:PF00614; PLDc; 2. TMhelix=1 Signal peptide probability: 1.0; Family membership.
       0.618
azo3494
Conserved hypothetical membrane protein. Homology to CV0155 of Chromobacterium violaceum of 69% (trembl|Q7P1Q8). Has PF03653, Uncharacterised protein family (UPF0093);IPR005265, Cons_hypoth701:It appears the conserved hypothetical integral membrane proteins of this family are found only in gram negative bacteria and their function is unknown. No signal peptide. 4 TMHs; Conserved hypothetical protein.
  
  
  0.587
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 0.575
hemF
HemF protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.573
hemN
Oxygen-independent coproporphyrinogen III oxidase. ANAEROBIC TRANSFORMATION OF COPROPORPHYRINOGEN-III INTO PROTOPORPHYRINOGEN-IX. hemN: oxygen-independent coproporphyrinogen III oxidase; High confidence in function and specificity.
    
 0.531
azo1750
Hypothetical membrane protein. No homology of the entire protein to the data bank. Has DUF1328(Protein of Unknown family) domain. PF07043;IPR009760; This family consists of several hypothetical bacterial proteins of around 50 residues in length. The function of this family is unknown. no signal peptide. 3 TMHs.
 
     0.503
azo1759
Conserved hypothetical membrane protein. Homology to Avin02003353 of Azotobacter vinelandii of 48% (gi|53610930|ref|ZP_00342175.1|(NBCI ENTREZ)). No domains predicted. signal peptide. 7 TMHs; Conserved hypothetical protein.
 
     0.482
azo2630
Cobalamin biosynthesis protein, putative; CobN Magnesium Chelatase family protein, by similarity; Family membership.
     
 0.481
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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