STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mucD3Probable serine protease MucD. Homology to mucD of P. aeruginosa of 40% (trembl|Q57155). InterPro: Serine proteases trypsin family (IPR001254); Chymotrypsin serine protease family (S1) (IPR001314); HtrA/DegQ protease family (IPR001940); PDZ domain (also known as DHR or GLGF) (IPR001478) Pfam: Trypsin; PDZ domain (also known as DHR or GLGF) signal peptide no TMHs TIGR00292: thiazole biosynthesis enzyme; High confidence in function and specificity. (472 aa)    
Predicted Functional Partners:
glpK
Probable glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.828
azo1761
Hypothetical protein, Shares 45% similarity with hypothetical protein [Chromobacterium violaceum]TrEMBL Q7NY28. Signal Peptide present. No TMH's reported. Has pfam05359, DUF748, Domain of Unknown Function (DUF748); Specificity unclear.
   
 
 0.820
azo1762
Conserved hypothetical membrane protein. Homology to XCC0079 of Xanthomonas campestris (trembl|Q8PEA2(SRS)). InterPro:IPR002549; UPF0118. Pfam PF01594; domain of DUF20 present. no signal peptide. 8 TMHs; Conserved hypothetical protein.
       0.773
rseA
Putative sigma-E factor, negative regulatory protein,; High confidence in function and specificity.
  
 
 0.703
azo2279
Conserved hypothetical protein. Homology to Avin02000067 of Azotobacter vinelandii of 50% (gi|23105742|ref|ZP_00092196.1|(NBCI ENTREZ)). InterPro: Ankyrin-repeat. The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids.The ankyrin fold appears to be defined by its structure rather than its function since there is no specific sequence or structure which is universally recognised by it. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [...]
   
  0.686
ank1
Putative ankyrin repeat harbouring exported protein; Hypothetical protein KIAA1223 (Fragment). TREMBL:Q8XYH0:35% identity; TREMBL:Q7VXC9:35% The ankyrin repeat is one of the most common protein-protein interaction motifs in nature. Ankyrin repeats are tandemly repeated modules of about 33 amino acids. They occur in a large number of functionally diverse proteins mainly from eukaryotes.Each Ankyrin repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90 angle. The repeats stack together to form an L-shaped structure InterPro [...]
   
  0.683
tnkS
Putative tankyrase type protein; Tankyrase 2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein). May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1 and thereby contribute to the regulation of telomere length. TREMBL:Q800E0:34%; Q8YTG9:36% identity. InterPro: Ankyrin-repeat Mop: molybdenum-pterin binding domain Presence of signal peptide (SignalP) but absence of transmembrane helices; Function [...]
    
  0.680
azo3776
Conserved hypothetical membrane protein. Homology to ebA2790 of Azoarcus sp. EbN1 of 31% (gnl|keqq|eba:ebA2790(KEGG)). No domains predicted. no signal peptide. 2 TMHS; Conserved hypothetical protein.
    
  0.680
lepB
LepB protein; Signal peptidase I (EC 3.4.21.89) (SPase I) (Leader peptidase I). SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by one or two N-terminal transmembrane domains, with the main part of the protein protuding in the periplasmic space. SPase I can cleave N-terminal leader sequences of nonlipoprotein that are exported by the SecYEG pathway or the twin arginine translocation (Tat) pathway. Pfam: Peptidase_S26 probable 2 TMH no signal peptide; High confidence in function and specificity.
    
 0.649
rpsP
30S ribosomal protein S16; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bS16 family.
  
 
   0.576
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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