STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
azo1770Conserved hypothetical DnaK suppressor protein. Homology to BPSS2280 of Burkholderia pseudomallei of 34% (gnl|keqq|bps:BPSS2280(KEGG). Has PF01258, Prokaryotic dksA/traR C4-type zinc finger; IPR000962 Znf_DskA/TraR; The dksA gene product suppresses the temperature-sensitive growth and filamentation of a dnaK deletion mutant of Escherichia coli. Gene knockout and deletion experiments have shown the gene to be non-essential, mutations causing a mild sensitivity to UV light, but not affecting DNA recombination. The protein contains a C-terminal region thought to fold into a 4-cysteine zin [...] (135 aa)    
Predicted Functional Partners:
cioA
Probable cyanide insensitive terminal oxidase,subunit I Homology to cioA of P. aeruginose of 44% (TREMBL:O07440) InterPro: Cytochrome bd ubiquinol oxidase subunit I (IPR002585) Pfam: Bacterial cytochrome ubiquinol oxidase no signal peptide no TMHs; High confidence in function and specificity.
       0.741
cioB
Probable cyanide insensitive terminal oxidase,subunit II. Homology to cioB of P. aeruginosa of 40% (trembl|O07441). Tigrfam: cydB: cytochrome d ubiquinol oxidase, subunit II Pfam: cytochrome oxidase, subunit II no signal peptide 8 TMHs; High confidence in function and specificity.
       0.741
rpoC
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.725
rpoB
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.724
hfq
RNA-binding regulatory protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.711
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.610
rpoA
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.595
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.588
azo0455
Putative cobalmin snthesis protein; This family of proteins contains P47K, a Pseudomonas chlororaphis protein needed for nitrile hydratase expression, and the cobW gene product, which may be involved in cobalamin biosynthesis in Pseudomonas denitrificans [1]. TREMBL:Q8YJP6: 40% identity, 54% similarity. Pfam:PF02492; Cobalmine synthesis protein; pfkB family carbohydrate kinase; FAD binding domain. TIGRFAM:proC: pyrroline 5 carboxylate reductase. mobB: molybdopterin-guanine dinucleotide; Family membership.
  
  
 0.518
azo1210
Putative GTPase; TREMBLnew:CAE26305: 46% identity, 65% similarity. sprot:YJIA_ECOLI, 33% identity, 55% similarity Hypothetical protein. Pfam:cobW: Cobalmine synthesis protein; ABC_tran TIGRFAM: MMR_HSR1- GTPASE of unknown function InterPro: Cobalamin synthesis protein/P47K mobB: molybdopterin-guanine dinucleotid; Conserved hypothetical protein.
  
  
 0.518
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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