STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1783Conserved hypothetical membrane protein. Homology to ebA6946 of Azoarcus sp. EbN1 of 64% (gnl|keqq|eba:ebA6946(KEGG)). Pfam: Pospholipase D, active site motife; DedA family. no signal peptide. 6 TMHs; Conserved hypothetical protein. (759 aa)    
Predicted Functional Partners:
azo1782
Conserved hypothetical protein. Homology to mlr2853 of M. loti of 31% (trembl|Q98HI7). Tigrfam: xth: exodeoxyribonuclease III (xth). All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Pfam: AP endonuclease family I. no signal peptide. no TMHs.
 
 
 0.959
aas
AAS bifunctional protein [Includes: 2-acylglycerophosphoethanolamine acyltransferase (2-acyl-GPE acyltransferase); Acyl-acyl carrier protein synthetase (Acyl-ACP synthetase)]. PLAYS A ROLE IN LYSOPHOSPHOLIPID ACYLATION. TRANSFERS FATTY ACIDS TO THE 1-POSITION VIA AN ENZYME-BOUND ACYL-ACP INTERMEDIATE IN THE PRESENCE OF ATP AND MG(2+). ITS PHYSIOLOGICAL FUNCTION IS TO REGENERATE PTDETN FROM 2-ACYL-GPE FORMED BY TRANSACYLATION REACTIONS OR DEGRADATION BY PHOSPHOLIPASE A1, TREMBL:Q8FEA6 (52% identity); SWISSPROT:P31119 (52% identity). Pfam (PF00501): AMP-binding enzyme. Pfam (PF01553): Ac [...]
   
 0.953
azo0138
Conserved hypothetical protein.Similarity to b.subtilis bmru and to synechocystis pcc 6803 sll0036. Identities = 29/85 (34%) Entry name SWISSPROT:YEGS_ECOLI Prim. accession # P76407 InterPro IPR005218; Cons_hypoth147. IPR001206; DAGKc. Pfam PF00781; DAGKc; 1. Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0.
 
 
 0.783
bfr3
Bacterioferritin (BFR) (Cytochrome B-1) (Cytochrome B-557). In E. coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central cavity of about 8 nm diameter.X-ray crystallographic studies have revealed a close structural similarity between BFR and the ferritins, a family of iron-storage proteins found in both eukaryota and prokaryota. Key role in iron homeostasis.InterPro: Bacterioferritin. Non-secretory protein bfr: bacterioferritin; High confidence in function and specificity.
       0.757
azo1781
Conserved hypothetical protein. Homology to map2952a of M. paratuberculosis of 51% (AAS05269). Pfam: CahB; Rho terminator factor, N-terminal. domain no signal peptide. no TMHs.
       0.752
azo1786
Conserved hypothetical phosphoesterase family protein. Homology to ebA6940 of Azoarcus sp. EbN1 of 65% (gnl|keqq|eba:ebA6940(KEGG)). InterPro IPR008934; AcPase_VanPerase. IPR000326; PA_PTPase. Pfam PF01569; PAP2; Number of predicted TMHs: 3#. Prediction: Non-secretory protein Signal peptide probability: 0.000; Conserved hypothetical protein.
   
 0.733
pssA
This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis catalyzing the reaction CDP-diacylglycerol + L-serine = CMP + L-1-phosphatidylserine. Entry name:-SWISSPROT:PSS_HELPY identity:- 34% InterPro:-IPR000462; CDP-OH_P_trans. IPR004533; PssA. Pfam:- PF01066; CDP-OH_P_transf; 1. Number of predicted TMHs: 6 Prediction: Non-secretory protein Signal peptide probability: 0.047(YES); Family membership; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
    
 0.723
psD
Probable phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
  
 0.711
azo0788
Probable acyltransferase; Acyl-[acyl-carrier protein] can also acts as acyl donor.The animal enzyme is specific for the transfer of unsaturated fatty acyl groups. Catalytic Activity:-Acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate. Entry name TREMBL:Q82VB2 Prim. accession # Q82VB2 InterPro:-IPR002123; Acyltransferase. Pfam:- PF01553; Acyltransferase; 1. Identity:- 56% Prediction: Signal peptide Signal peptide probability: 0.907 Number of predicted TMHs: 1; Family membership.
   
 0.707
dgkA
Probable diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
    
 0.703
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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