STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
azo1792Conserved hypothetical membrane protein. Homology to xcc0923 of X. campestris of 46% (trembl|Q8PC30). InterPro: Uncharacterized protein family UPF0003 (IPR006685). Pfam: Mechanosensitive ion chanell. Mechanosensitive (MS) channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation. no signal peptide. 5 TMHs; Conserved hypothetical protein. (376 aa)    
Predicted Functional Partners:
azo1795
Conserved hypothetical protein; DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein; Specificity unclear.
 
     0.862
azo1791
Conserved hypothetical secreted protein. Homology to ebA6930 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH reported present; Conserved hypothetical protein.
 
     0.823
glgB2
14-alpha-glucan branching enzyme (Glycogen branching enzyme)(BE) (14-alpha-D-glucan:14-alpha-D-glucan 6-glucosyl- transferase). Catalyzes the formation of the alpha-16-glucosidic linkages in glycogen by scission of a 14-alpha-linked oligosaccharide from growing alpha-14-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-16 position. 36% Alpha_amyl_cat.IPR006407;GlgB.IPR004193;Glyco_hydro_13N. Pfam:PF00128; Alpha-amylase; 1.PF02922; Isoamylase_N; 1. TIGRFAMs:TIGR01515; branching_enzym; 1; High confidence in function and specificity.
       0.780
azo1793
Conserved hypothetical protein.Weak Homology with Hits in the Database. Has IPR000967 Znf_NFX1;(SMART;SM00438)This domain is presumed to be a zinc binding domain. The following pattern describes the zinc finger: C-X(1-6)-H-X-C-X3-C(H/C)-X(3-4)-(H/C)-X(1-10)-C, where X can be any amino acid, and numbers in brackets indicate the number of residues. The two position can be either his or cys. This domain is found in the human transcriptional repressor NK-X1, a repressor of HLA-DRA transcription; the Drosophila shuttle craft protein, which plays an essential role during the late stages of e [...]
       0.775
glgX
Putative glycogen debranching enzyme; Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
       0.775
gcvP
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
    0.648
treZ
Malto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1; Specificity unclear.
 
     0.588
azo1799
The first part of the protein (2202 bases) is 37% Glyco_hydro_77. Pfam:PF02446; 4A_glucanotrans; 1.TIGRFAMs:TIGR00217; malQ; 1. GO:5975/4134. The second part of the protein (from the base 2128 to the end) is 39%; Function unclear; ORF5.
       0.555
glgC
Putative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
       0.517
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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