STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
glgCPutative glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (404 aa)    
Predicted Functional Partners:
glgA
Putative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
 
 0.999
glgX
Putative glycogen debranching enzyme; Glycogen operon protein GlgX homolog.Hydrolyzes the alpha-1,6-glucosidic linkages in glycogen which has first been partially depolymerized by phosphorylase. Shows only very little activity with native glycogen. 46% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.F02922; isoamylase_N; 1; High confidence in function and specificity; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.995
glgB2
14-alpha-glucan branching enzyme (Glycogen branching enzyme)(BE) (14-alpha-D-glucan:14-alpha-D-glucan 6-glucosyl- transferase). Catalyzes the formation of the alpha-16-glucosidic linkages in glycogen by scission of a 14-alpha-linked oligosaccharide from growing alpha-14-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-16 position. 36% Alpha_amyl_cat.IPR006407;GlgB.IPR004193;Glyco_hydro_13N. Pfam:PF00128; Alpha-amylase; 1.PF02922; Isoamylase_N; 1. TIGRFAMs:TIGR01515; branching_enzym; 1; High confidence in function and specificity.
 
 0.985
azo1799
The first part of the protein (2202 bases) is 37% Glyco_hydro_77. Pfam:PF02446; 4A_glucanotrans; 1.TIGRFAMs:TIGR00217; malQ; 1. GO:5975/4134. The second part of the protein (from the base 2128 to the end) is 39%; Function unclear; ORF5.
 
  
 0.984
treZ
Malto-oligosyltrehalose trehalohydrolase(MTHase) (4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase) (Maltooligosyl trehalose trehalohydrolase).Involved in the trehalose biosynthesis,hydrolysing alpha-(1->4)-d-glucosidic linkage in 4-alpha-d-{(1->4)-alpha-d-glucanosyl}(n) trehalose to yield trehalose and alpha-(1->4)-d-glucan. 42% Alpha_amyl_cat.IPR004193; Glyco_hydro_13N. Pfam:PF00128; alpha-amylase; 1.PF02922; isoamylase_N; 1; Specificity unclear.
 
 
 0.982
pgm
Phosphomannomutase/phosphoglucomutase (PMM / PGM). The phosphomannomutase activity produces a precursor for alginate polymerization. This enzyme participates in both the breakdown and synthesis of glucose.Catalytic activity: Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 58% PG/PMM_mutase.IPR005844; PG_PMM_ABAI.IPR005845; PG_PMM_ABAII.IPR005846; PG_PMM_ABAIII.IPR005843; PG_PMM_C. Pfam:PF02878; PGM_PMM_I; 1.PF02879; PGM_PMM_II; 1.PF02880; PGM_PMM_III. PF00408; PGM_PMM_IV; 1; High confidence in function and specificity.
  
 
 0.977
glgB1
Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 0.970
argG
ArgG protein; Argininosuccinate synthase, argG. Similar to SWISSPROT:ASSY_NITEU (81%). Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate. InterPro (PF00764): Argininosuccinate synthase InterPro (TIGR00032): Argininosuccinate synthase; High confidence in function and specificity.
  
 
 0.951
galU
UTP--glucose-1-phosphate uridylyltransferase 1 (EC 2.7.7.9) (UDP- glucose pyrophosphorylase 1) (UDPGP 1) (Alpha-D-glucosyl-1-phosphate uridylyltransferase 1) (Uridine diphosphoglucose pyrophosphorylase 1). InterPro: ADP-glucose pyrophosphorylase ispD: 4-diphosphocytidyl-2C-methyl-D-er; High confidence in function and specificity.
     
 0.945
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
  
  
 0.908
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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