Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
azo1804Membrane-anchored glycosyltransferase; Hypothetical 55.3 kDa protein in thcA 5region (ORF1); High confidence in function and specificity. (326 aa)    
Predicted Functional Partners:
azo1807
Heptose phosphatase; Hypothetical protein yaeD; High confidence in function and specificity.
     0.955
azo1809
Glycosyltransferase; Hypothetical protein Rv0486/MT0504/Mb0496. InterPro: Glycosyl transferases group 1; Specificity unclear.
 
  
 0.949
azo1803
Conserved hypothetical glycosyltransferase. Homology to ebA6914 of Azoarcus sp. EbN1 of 72% (gnl|keqq|eba:ebA6914(KEGG)). Pfam: Glycos_transf_1. Interpro: Glycosyl transferase, group 1. Proteins containign this domain transfer UDP, ADP, GDP or CMP linked sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. The bacterial enzymes are involved in various biosynthetic processes that include exopolysaccharide biosynthesis,lipopolysaccharide core biosynthesis and the biosynthesis of the slime polysaccaride colanic acid. No signal peptide. No TM [...]
 
  
 0.939
waaF1
ADP-heptose--LPS heptosyltransferase II (EC 2.-.-.-). pdxJ: pyridoxal phosphate biosynthetic; High confidence in function and specificity.
 
   
 0.925
azo1805
Hypothetical conserved hypothetical cabamoyltransferase. Homology to sco6480 of S. coelicolor of 49% (trembl|Q8CJN9). Pfam: Carbamyltransferase. no signal peptide. no TMHS; Conserved hypothetical protein.
 
   
 0.923
azo1808
The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases,TREMBL:Q8YLL2 (35% identity); TREMBL:Q9HWN3 (37% identity). InterPro (IPR002198): Short-chain dehydrogenase/reductase (SDR). InterPro (IPR002347): Glucose/ribitol dehydrogenase. Pfam (PF00106): Short chain dehydrogenase; Specificity unclear.
 
     0.858
azo1802
Putative dTDP-glucose 4,6-dehydratase; 67% Epimerase_Dh. Pfam: PF01370; Epimerase; 1. No signal peptide; Family membership.
    
 0.757
azo3907
Conserved hypothetical protein. Homology to xac4125 of X. axonopodis of 42% (trembl|Q8PF60). Domain structure: 5 x TRP, 50 aa - 83 aa; 84 aa - 117 aa; 118 aa - 151 aa; 152 aa - 182 aa; 186 aa - 219 aa. InterPro: TPR repeat (IPR001440); SAM (and some other nucleotide) binding motif (IPR000051). Pfam: TPR daomian. no signal peptide. no TMHs.
  
 
 0.755
azo0531
Conserved hypothetical secreted protein. Homology to PA2778 of P.aeruginosa of 39% (trembl|Q9I065(SRS)) Has Signal Peptide. No TMH present. Has PF03412:Peptidase C39 family;Lantibiotic and non-lantibiotic bacteriocins are synthesised as precursor peptides containing N-terminal extensions (leader peptides) which are cleaved off during maturation. Most non-lantibiotics and also some lantibiotics have leader peptides of the so-called double-glycine type. These leader peptides share consensus sequences and also a common processing site with two conserved glycine residues in positions -1 an [...]
  
 
 0.744
xanB
Probable xanthan biosynthesis protein XanB. Homology to xanB of X. campestris of 60% (sprot|XANB_XANCP(SRS)) Xanthan biosynthesis protein XanB is a multifunctional enzyme including Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphomannose isomerase) (PMI) (Phosphohexomutase)and Mannose-1-phosphate guanylyl transferase (GDP) (EC 2.7.7.22) (GDP-mannose pyrophosphorylase) (GMP). InterPro: ADP-glucose pyrophosphorylase (IPR005835); Mannose-6-phosphate isomerase type II (IPR001538) Pfam: Nucleotidyl transferase, Mannose-6-phosphate isomerase no signal peptide no TMHs; Family membership.
  
 
 0.715
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.