STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1818Exoribonuclease II; Putative ribonuclease RNASE BN (RBN)Protein, 31% identity (44% similarity) to TrEMBL; Q8XPH6. Has PF03631; Ribonuclease BN-like family;IPR004664, RNase_BN;This family contains integral membrane proteins with 5 to 6 predicted transmembrane spans. The family include ribonuclease BN that is involved in tRNA maturation P32146. This family of proteins does not seem to contain any completely conserved polar residues that would be expected in a nuclease enzyme, suggesting that many members of this family may not have this catalytic activity; Family membership. (306 aa)    
Predicted Functional Partners:
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
 
   
 0.660
azo1795
Conserved hypothetical protein; DNA topoisomerase I (EC 5.99.1.2). The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. cbiB: cobalamin biosynthesis protein; Specificity unclear.
  
    0.546
azo1773
Conserved hypothetical protein. Homology to an orf of P. putida of 58% (trembl|O68643). no TMHs. no signal peptide. No domains predicted.
  
     0.536
azo1814
Conserved hypothetical protein. Homology to ebD123 of Azoarcus sp. EbN1 of 50% (gnl|keqq|eba:ebD123(KEGG)). No domains predicted. No TMHs. No signal peptide.
       0.532
azo1820
Conserved hypothetical protein. Homology to BB2852 of B.bronchiseptica of 53% (tremble:Q7WIJ9). Has pfam05239, PRC, PRC-barrel domain. The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins c [...]
 
     0.530
azo1815
Hypothetical membrane protein. No homology of the entire protein with the data bank. No domains predicted. No signal peptide. 2 TMHs.
       0.526
azo1816
Hypothetical membrane protein. No homology to the data bank. No domains predicted No signal peptide 2 TMHs.
       0.526
azo1819
Hypothetical protein. Homology to dr0392 of D. radiodurans of 25% (trembl|Q9RXC3) Smart: Bacterial OsmY and nodulation domain (BON). The BON domain is typically ~60 residues long and has an alpha/beta predicted fold. There is a conserved glycine residue and several hydrophobic regions. This pattern of conservation is more suggestive of a binding or structural function rather than a catalytic function. Most proteobacteria seem to possess one or two BON-containing proteins, typically of the OsmY-type proteins. no signal peptide no TMHs; High confidence in function and specificity.
       0.466
azo1791
Conserved hypothetical secreted protein. Homology to ebA6930 of Azoarcus sp. EbN1 of 37% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH reported present; Conserved hypothetical protein.
  
    0.459
azo1741
Putative DNA-ligase like protein Rv0938/MT0965. dnl1: DNA ligase I ATP-dependent; Specificity unclear; ORF4.
 
     0.453
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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