STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mauGDi-heme cytochrome c peroxidase MauG, required for the synthesis of the tryptophan tryptophylquinone (TTQ) prosthetic group of MADH in P.denitrificans. INVOLVED IN METHYLAMINE METABOLISM. ESSENTIAL FOR THE MATURATION OF THE BETA SUBUNIT OF MADH PRESUMABLY VIA A STEP IN THE BIOSYNTHESIS OF TRYPTOPHAN TRYPTOPHYLQUINONE (TTQ) THE COFACTOR OF MADH. urease_gam: urease gamma subunit; High confidence in function and specificity. (460 aa)    
Predicted Functional Partners:
azo1832
Conserved hypothetical secreted protein. Homology ebA6930 of Azoarcus EbN1 of 31% (gnl|keqq|eba:ebA6930(KEGG)). No domains predicted. Signal peptide present. No TMH present; Conserved hypothetical protein.
 
     0.789
maub
Methylamine dehydrogenase heavy chain precursor (MADH):- Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. Entry name SWISSPROT:DHMH_METEX Prim. accession # Q49124 Identities = 100/339 (29%) Prediction: Signal peptide Signal peptide probability: 1.000 Number of predicted TMHs: 0; Family membership.
   
 
 0.711
mauA
Probable methylamine dehydrogenase. Homology to mauD of P. denifrificans of 45% (CAA67190) carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin. InterPro: Methylamine dehydrogenase L subunit (IPR004229) Pfam: Methylamine dehydrogenase, L chain signal peptide no TMHs; High confidence in function and specificity.
   
   0.704
azo1724
Conserved hypothetical protein. Homology to SMA1058 of S.meliloti of 48% (trembl:Q92ZB7). No domains predicted. No signal peptide. No TMHs.
  
     0.654
azo1735
Conserved hypothetical protein. Homology to rO1139 of S. meliloti of 48% (trembl|Q92QZ6). No domains predicted. No signal peptide. No TMHs.
  
     0.497
alkA
DNA-3-methyladenine glycosylase 1 (3-methyladenine DNA glycosidase 1) (3MEA DNA glycosylase 1). HYDROLYSIS OF THE DEOXYRIBOSE N-GLYCOSIDIC BOND TO EXCISE 3-METHYLADENINE OR 7-METHYLADENINE FROM THE DAMAGED DNA POLYMER FORMED BY ALKYLATION LESIONS. CAN RELEASE ETHYLATED AND PROPYLATED BASES FROM DNA IN ADDITION TO 3-METHYLADENINE. TIGR00274: glucokinase regulator-related; High confidence in function and specificity.
       0.488
azo1820
Conserved hypothetical protein. Homology to BB2852 of B.bronchiseptica of 53% (tremble:Q7WIJ9). Has pfam05239, PRC, PRC-barrel domain. The PRC-barrel is an all beta barrel domain found in photosystem reaction centre subunit H of the purple bacteria and RNA metabolism proteins of the RimM group. PRC-barrels are approximately 80 residues long, and found widely represented in bacteria, archaea and plants. This domain is also present at the carboxyl terminus of the pan-bacterial protein RimM, which is involved in ribosomal maturation and processing of 16S rRNA. A family of small proteins c [...]
  
     0.457
qhpB
Probable quinohemoprotein amine dehydrogenase,alpha subunit. Homology to qhpB of P.putida of 50% (gi|34809688|pdb|1PBY|B(PDB (RCSB))). Quinoproteins are a class of amine-oxidising enzymes that catalyse the oxidation of biological amines, using quinone as a redox cofactor to store reducing equivalents. Quinohemoprotein amine dehydrogenase (QH-AmDH) from bacteria represents a new class of quinoproteins that contains both quinone and one or two hemes as redox active groups. The presence of extra redox active groups allows for intramolecular electron transfer. QH-AmDH is a heterotrimeric e [...]
   
 
 0.450
azo2935
Conserved hypothetical protein TMHMM2 reporting the presence of 1 TMH's. No Signal peptide present. Has 2 WD40 repeats;SMART;SM00320, Beta-transducin (G-beta) is one of the three subunits (alpha, beta, and gamma) of the guanine nucleotide-binding proteins (G proteins) which act as intermediaries in the transduction of signals generated by transmembrane receptors (see IPR001632). The alpha subunit binds to and hydrolyzes GTP; the functions of the beta and gamma subunits are less clear but they seem to be required for the replacement of GDP by GTP as well as for membrane anchoring and re [...]
   
 
 0.450
azo3207
Conserved hypothetical secreted protein. Homology to PA1688 of Pseudomonas aeruginosa of 54% (trembl|Q9X6R1(SRS)). No domains predicted. Signal p reporting signal peptide present. NO TMH present; Conserved hypothetical protein.
   
 
 0.450
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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