Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene neighborhood
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[Homology]
Score
crtB1Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 30% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership. (281 aa)    
Predicted Functional Partners:
azo1885
Putative oxidoreductase precursor, 27% identity (38% similarity) to TrEMBL;Q6N3F3. TrEMBL;Q9RI54. Has PF00070;Pyridine nucleotide-disulphide oxidoreductase; IPR001327 FAD_pyr_redox:This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain. Has PF01593,Flavin containing amine oxidoreductase;(IPR002937,Amino_oxidase):This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). T [...]
 
     0.909
crtI
Phytoene dehydrogenase (EC 1.14.99.-) (Phytoene desaturase). Phytoene dehydrogenase (phytoene desaturase) is an enzyme of carotenoid biosynthesis that converts phytoene into zeta-carotene via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene, TREMBL:Q8XYC4 (50% identity); SWISSPROT:P06108 (26% identity). InterPro (IPR008150): Bacterial-type phytoene dehydrogenase Pfam (Phytoene_dh): Phytoene dehydrogenase related enzyme; High confidence in function and specificity.
 
 
 0.849
crtB2
Putative phytoene synthase. Homology to crtB of Synechococcus sp. of 35% (SWISSPROT:CRTB_SYNP7 Is involved in the synthesis of carotenoids. Catalyzes the reaction from prephytoene diphosphate to phytoene. Pfam: Squalene/phytoene synthase no singal peptide no TMHs; Family membership.
 
   
0.760
acbB
Putative dTDP-glucose 4-6-dehydratase; dTDP-glucose 4,6-dehydratase, AcbB,probably involved in the biosynthesis of the acarviose moiety of the alpha-glucosidase inhibitor acarbose. Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. 30% dTDP_gluc_dehyt.IPR001509; Epimerase_Dh. Pfam:PF01370; Epimerase; 1. TIGRFAMs:TIGR01181; dTDP_gluc_dehyt; 1; High confidence in function and specificity.
   
 0.759
wbnF
Putative nucleotide sugar epimerase; Probably involved in the biosynthesis of exopolysaccharides. 68% Epimerase_Dh.IPR008089; Nuc_sugar_epim. Pfam:PF01370; Epimerase; 1; High confidence in function and specificity.
   
 0.759
azo1802
Putative dTDP-glucose 4,6-dehydratase; 67% Epimerase_Dh. Pfam: PF01370; Epimerase; 1. No signal peptide; Family membership.
   
 0.759
azo1826
NADH dehydrogenase (ubiquinone); 39%.
   
 0.759
azo2368
Conserved hypothetical protein. Homology to RSc3335 of Ralstonia solanacearum of 52% (gnl|keqq|rso:RS02569(KEGG)). No domains predicted. No TMHs. No signal peptide.
   
 0.759
azo3495
Conserved hypothetical protein; 55%; Specificity unclear.
   
 0.759
rfaD
Putative ADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
   
 0.759
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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