azo1886 protein (Azoarcus sp. BH72) - STRING interaction network

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azo1886

Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl|Q8XXV5). no domain predicted. no signal peptide. no TMHs. (374 aa)

Predicted Functional Partners:

azo1887

0.711

lpdA

0.696

odhA

0.638

gor

0.572

odhL

0.572

bioF

0.487

bioH

0.482

bioA

0.481

bioC1

0.481

bioD

0.481

Your Current Organism:

Azoarcus sp. BH72

NCBI taxonomy Id: 62928
Other names: A. sp. BH72

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
azo1886	azo1887	azo1886	azo1887	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	0.711
azo1886	bioA	azo1886	azo1888	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.481
azo1886	bioC1	azo1886	azo1891	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Biotin synthesis protein bioC. bioc is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin; Specificity unclear.	0.481
azo1886	bioD	azo1886	azo1892	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.481
azo1886	bioF	azo1886	azo1889	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.	0.487
azo1886	bioH	azo1886	azo1890	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	BioH protein.Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). Seems to be implicated in the early steps of biotin biosynthesis; Function unclear.	0.482
azo1886	gor	azo1886	azo0659	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Probable glutathione-disulfide reductase. Homology to gor of E. coli of 53% (sprot\|GSHR_ECOLI). Maintain high levels of reduced glutathione in the cytosol. InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); NAD binding site (IPR000205); Pyridine nuclotide-disulfide oxidoreductase dimerisation doamin (IPR004099); Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100) Pfam: Pyridine nuccleotide-dusulfphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase dimerisation domain no signal peptide no TMHs; High confidence in function and [...]	0.572
azo1886	lpdA	azo1886	azo1371	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Dihydrolipoamide dehydrogenase. Homology to lpdA of N. meningitides of 70% (trembl\|Q59099). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3) (BY SIMILARITY). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); biotin/Lipoyl attachment (IPR000089) [...]	0.696
azo1886	odhA	azo1886	azo1555	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Probable 2-oxoglutarate dehydrogenase. Homology to odhA of A. eutrophus of 63% (sprot\|ODO1_ALCEU). THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE DEHYDROGENASE (E1) DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: Dehydrogenase E1 component (IPR001017); Transletolase (IPR005474) Tigrfam: 2oxo_dh_E1: 2-oxoglutarate dehydrogenase, E1 component Pfam: Dehydrogenase E1 component, Transketolas, pyridine binding domain [...]	0.638
azo1886	odhL	azo1886	azo1557	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	Probable dihydrolipoamide dehydrogenase. Homology to odhL of A. eutrophus of 68% (sprot\|DLDH_ALCEU). THE BRANCHED-CHAIN ALPHA-KETO DEHYDROGENASE COMPLEX CATALYZES THE OVERALL CONVERSION OF ALPHA-KETO ACIDS TO ACYL-COA AND CO(2). IT CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: BRANCHED-CHAIN ALPHA-KETO ACID DECARBOXYLASE (E1) LIPOAMIDE ACYLTRANSFERASE (E2) AND LIPOAMIDE DEHYDROGENASE (E3). InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (IPR001327); Pyridine nucleotide-disulphide oxidoreductase, classI (IPR001100); Pyridine nucleotide-disulphide oxidoreducta [...]	0.572
azo1887	azo1886	azo1887	azo1886	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	0.711
azo1887	bioA	azo1887	azo1888	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.612
azo1887	bioC1	azo1887	azo1891	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	Biotin synthesis protein bioC. bioc is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin; Specificity unclear.	0.555
azo1887	bioD	azo1887	azo1892	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.588
azo1887	bioF	azo1887	azo1889	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.	0.572
azo1887	bioH	azo1887	azo1890	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	BioH protein.Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily). Seems to be implicated in the early steps of biotin biosynthesis; Function unclear.	0.572
bioA	azo1886	azo1888	azo1886	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Conserved hypothetical protein. Homology to rsc2008 of R. solanacearum of 59% (trembl\|Q8XXV5). no domain predicted. no signal peptide. no TMHs.	0.481
bioA	azo1887	azo1888	azo1887	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Conserved hypothetical protein. Homology to RS03577 of R.solanacearum of 66% (tremble:Q8XXV4). Has PF03883,Protein of unknown function (DUF328); IPR005583; Members of this family are functionally uncharacterised. They are about 250 amino acids in length. No signal peptide. No TMHs; Belongs to the UPF0246 family.	0.612
bioA	bioC1	azo1888	azo1891	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Biotin synthesis protein bioC. bioc is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin; Specificity unclear.	0.875
bioA	bioD	azo1888	azo1892	Adenosylmethionine--8-amino-7-oxononanoate transaminase; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) (7,8-diamino-pelargonic acid aminotransferase) (DAPA aminotransferase). TGIRFAM: bioA: adenosylmethionine--8-amino-7-oxononanoate transaminase; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.	0.998