Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dctD2C4-dicarboxylate transport transcriptional regulatory protein,; High confidence in function and specificity. (447 aa)    
Predicted Functional Partners:
dctB2
Sensor histidine kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.
 
 
  0.962
dctB1
Sensor histidine kinase; C4-dicarboxylate transport sensor protein,; High confidence in function and specificity.
 
 
  0.826
rpoN2
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.796
rpoN1
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.794
azo1916
Conserved hypothetical secreted protein. Homology to blr1303 of B. japonicum of 38% (trembl|Q89UV6(SRS)) No domains predicted. Signal peptide present. No TMH present; Conserved hypothetical protein.
       0.771
azo1917
Conserved hypothetical membrane protein. Homology to so0455 of S. oneidensis of 65% (trembl|Q8EJK8). Tigrfam: dctM: TRAP dicarboxylate transporter-DctM subunit. Pfam: TRAP C4-dicarboxylate transport (Dct) system permease DctM subunit. This domain represents a conserved region located towards the N terminus of the DctM subunit of the bacterial and archaeal TRAP C4-dicarboxylate transport (Dct) system permease. no signal peptide. 17 TMHs; Conserved hypothetical protein.
       0.768
azo2457
Putative sensory box histidine kinase,; Function unclear.
  
 0.746
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
  
 0.736
barA
Putative sensor-regulator protein,; Specificity unclear.
  
 0.728
azo2482
Putative hybrid sensor and regulator; Gene function unknown, no significant homology to proteins of known function. Typical domains for hybrid sensor and regulator are found. InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR001789 Response_reg. IPR008207 Hpt. IPR000014 PAS_domain. IPR001610 PAC. Pfam: PF00072 Response_reg. PF02518 HATPase_c. PF00512 HisKA. PF00989 PAS. PF00785 PAC. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00448 REC. SM00091 PAS SM00086 PAC. TIGRFAM: TIGR00229 PAS domain S-box. Signal P reporting signal pepti [...]
  
 0.728
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.