| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| azo1923 | etfB2 | azo1923 | azo1922 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | 0.698 |
| azo1923 | fumB | azo1923 | azo2415 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.762 |
| azo1923 | gabD2 | azo1923 | azo1920 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of P. aeruginosa of 62% (trembl|Q9RBF6) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. | 0.668 |
| azo1923 | gcdH1 | azo1923 | azo1924 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable glutaryl-CoA dehydrogenase; CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q98HG5 Prim. accession # Q98HG5 Identities = 253/397 (63%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_ [...] | 0.804 |
| azo1923 | gcdH2 | azo1923 | azo1930 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Glutaryl-CoA dehydrogenase mitochondrial precursor CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q88RH2 Prim. accession # Q88RH2 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number [...] | 0.805 |
| azo1923 | icmF | azo1923 | azo0696 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.720 |
| azo1923 | mutB | azo1923 | azo0685 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable Methylmalonyl-CoA mutase large subunit; FUNCTION: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates (By similarity). ACtivity:- (R)-2-Methylmalonyl-CoA = succinyl-CoA Entry name :- MUTB_PORGI Primary accession number :-Q59677 Identities = 467/679 (68%) InterPro :-IPR006159; Acid_CoA_mut_C. IPR006158; B12-binding. IPR006099; MMCoA_mutase. IPR006098; MMCoA_mutase_N. IPR006100; MMCoA_mutase_sub. Pfam PF02310; B12-binding; 1. PF01642; MM_CoA_mutase; 1. Prediction: Non-secretory protein Signal [...] | 0.711 |
| azo1923 | odhB | azo1923 | azo1556 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Dihydrolipoamide S-succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.814 |
| azo1923 | sucC | azo1923 | azo3333 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.799 |
| azo1923 | sucD | azo1923 | azo3332 | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | Probable succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.816 |
| etfB2 | azo1923 | azo1922 | azo1923 | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | 0.698 |
| etfB2 | gabD2 | azo1922 | azo1920 | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of P. aeruginosa of 62% (trembl|Q9RBF6) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. | 0.417 |
| etfB2 | gcdH1 | azo1922 | azo1924 | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | Probable glutaryl-CoA dehydrogenase; CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q98HG5 Prim. accession # Q98HG5 Identities = 253/397 (63%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_ [...] | 0.708 |
| etfB2 | gcdH2 | azo1922 | azo1930 | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | Glutaryl-CoA dehydrogenase mitochondrial precursor CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q88RH2 Prim. accession # Q88RH2 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number [...] | 0.708 |
| etfB2 | sucD | azo1922 | azo3332 | Electron transfer flavoprotein, beta subunit. Homology to etfB of B. japonicum of 71% (sprot|ETFB_BRAJA). The electron transfer flavoprotein serves as a specific electron acceptor for some dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)(By similarity). Pfam: Electron transfer flavoprotein beta subunit no signal peptide no TMHS; High confidence in function and specificity. | Probable succinyl-CoA synthetase, alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.577 |
| fumB | azo1923 | azo2415 | azo1923 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Conserved hypothetical protein. Homology to pa0446 of P. aeruginosa of 72% (trembl|Q9I672). Pfam: CAIB/BAIF family. no signal peptide. no TMHs. | 0.762 |
| fumB | gabD2 | azo2415 | azo1920 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable succinate-semialdehyde dehydrogenase [NAD(P)+]. Homology to gabD of P. aeruginosa of 62% (trembl|Q9RBF6) Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+. Pfam: Aldehyde dehydrogenase family no signal peptide no TMHs; High confidence in function and specificity. | 0.618 |
| fumB | icmF | azo2415 | azo0696 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.650 |
| fumB | mutB | azo2415 | azo0685 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable Methylmalonyl-CoA mutase large subunit; FUNCTION: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates (By similarity). ACtivity:- (R)-2-Methylmalonyl-CoA = succinyl-CoA Entry name :- MUTB_PORGI Primary accession number :-Q59677 Identities = 467/679 (68%) InterPro :-IPR006159; Acid_CoA_mut_C. IPR006158; B12-binding. IPR006099; MMCoA_mutase. IPR006098; MMCoA_mutase_N. IPR006100; MMCoA_mutase_sub. Pfam PF02310; B12-binding; 1. PF01642; MM_CoA_mutase; 1. Prediction: Non-secretory protein Signal [...] | 0.641 |
| fumB | sucC | azo2415 | azo3333 | Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable succinyl-CoA synthetase, beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.965 |