STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1925Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family. (314 aa)    
Predicted Functional Partners:
azo2367
Transcriptional regulator, LysR family,; Function unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.649
bdhR
Transcriptional regulator, LysR family,; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.635
azo1543
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.566
gltR
Probable transcriptional regulator, LysR family; HTH-type transcriptional regulator gltR. POSITIVE REGULATOR OF GLUTAMATE BIOSYNTHESIS (GLTAB GENES). NEGATIVELY REGULATES ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|GLTR_BACSU (33% Bacillus subtilis, HTH-type transcriptional regulator GltR) InterPro: IPR000847 HTH_LysR. IPR009058 Winged helix DNA-binding. Pfam: PF00126 Bacterial regulatory helix-turn-helix protein,lysR family. HTH reporting nucleic acid binding motif; High confidence in function and specificity.
  
     0.563
nac
Nitrogen assimilation regulatory protein nac (Nitrogen assimilation control protein). TRANSCRIPTIONAL ACTIVATOR FOR THE HUT PUT AND URE OPERONS AND REPRESSOR FOR THE GDH AND GLTB OPERONS IN RESPONSE TO NITROGEN LIMITATION. NEGATIVE REGULATOR OF ITS OWN EXPRESSION. Similar to SWISSPROT: sprot|NAC_KLEAE (30% Klebsiella aerogenes, nitrogen assimilation regulatory protein nac (nitrogen assimilation control protein)) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Specificity unclear.
  
     0.538
azo1926
Hypothetical protein. no homology over the entire protein. no domain structure no signal peptide no TMHs.
       0.520
azo2360
Transcriptional regulator, LysR family,; Specificity unclear; Belongs to the LysR transcriptional regulatory family.
  
     0.517
gcdH1
Probable glutaryl-CoA dehydrogenase; CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q98HG5 Prim. accession # Q98HG5 Identities = 253/397 (63%) InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_ [...]
       0.503
azo1281
Probable transcriptional regulator, LysR family proteins.57% Identity to TrEMBL;Q9HYK6, Q87XZ5, Q88MD6. Has PF03466, LysR substrate binding domain;IPR005119,LysR_subst; The structure of this domain is known and is IPR000847, HTH_LysR; Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family, the lysR family,groups together a range of proteins, including ampR, catM,catR, cynR, cysB, gltC, iciA, ilvY, irgB, lysR [...]
  
     0.457
azo3003
Conserved hypothetical transcriptional regulator,LysR family. Similar to SWISSPROT: sprot|NTCB_SYNP7 (18% Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2), nitrogen assimilation transcriptional activator NtcB) Pfam: PF00126 Bacterial regulatory helix-turn-helix protein, lysR family. HTH reporting nucleic acid binding motif; Family membership.
  
     0.428
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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