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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
abmCProbable enoyl-CoA hydratase; Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H2O. Entry name TREMBL:Q93FB6 Identities = 224/280 (80%) Prim. accession # Q93FB6 InterPro IPR001753; EnCoA_hydrtse. Pfam PF00378; ECH; 1. Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the enoyl-CoA hydratase/isomerase family. (281 aa)    
Predicted Functional Partners:
abmD
Putative acyl-CoA dehydrogenase; Catalysis of the reaction:- acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor. Entry name TREMBL:Q98BT9 Prim. accession # Q98BT9 InterPro IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. Number of predicted TMHs: 0; Family membership.
 
 0.985
gcdH2
Glutaryl-CoA dehydrogenase mitochondrial precursor CATALYZES THE OXIDATIVE DECARBOXYLATION OF GLUTARYL-COA TO CROTONYL-COA AND CO(2) IN THE DEGRADATIVE PATHWAY OF L-LYSINE L-HYDROXYLYSINE AND L-TRYPTOPHAN METABOLISM. IT USES ELECTRON TRANSFER FLAVOPROTEIN AS ITS ELECTRON ACCEPTOR. Entry name TREMBL:Q88RH2 Prim. accession # Q88RH2 InterPro IPR006089; Acyl-CoA_dh. IPR006090; Acyl-CoA_dh_C. IPR006091; Acyl-CoA_dh_M. IPR006092; Acyl-CoA_dh_N. IPR009075; AcylCoADH_C_like. IPR009100; AcylCoA_dehyd_NM. Pfam PF00441; Acyl-CoA_dh; 1. PF02770; Acyl-CoA_dh_M; 1. PF02771; Acyl-CoA_dh_N; 1. Number [...]
  
 0.908
azo1929
TREMBL:Q89PR6: 50% identity; 71% similarity Probable 4-hydroxybenzoyl-CoA thioesterase. InterPro:IPR008272; 4HBcoA_thiost_AS Pfam:4HBT:4-hydroxybenzoyl-CoA thioesterase TIGR00051: conserved hypothetical protein No transmembrane helices; Function unclear.
 
 
  0.899
abmE
Conserved hypothetical protein. Homology to orf5 of Azoarcus evansii of 78% (tremble:Q93FB4). Pfam: Endoribonuclease L-PSP. Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Previously thought to inhibit protein synthesis initiation. This protein may also be involved in the regulation of purine biosynthesis. No signal peptide. No TMHs.
 
     0.896
fadA2
Probable 3-ketoacyl-CoA thiolase; Activity:- acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA Entry name:- SWISSPROT:THIK_ECOLI Prim. accession # P21151 InterPro:- IPR002155; Thiolase. Pfam:-PF02803; Thiolase_C; 1. PF00108; Thiolase_N; 1. Identities = 177/400 (44%) Number of predicted TMHs: 0; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.881
paaG6
Putative enoyl-CoA hydratase paaG; Function:- Could possibly oxidizes fatty acids using specific components (By similarity). Activity:-(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O. Entry name:- SWISSPROT:PAAG_ECOLI InterPro:- IPR001753; EnCoA_hydrtse. Pfam:- PF00378; ECH; 1. Identities = 65/222 (29%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; Family membership.
 
  0.881
azo1927
Probable enoyl-CoA hydratase; Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2(or3)-enoyl-CoA + H2O. Entry name TREMBL:Q7VU52 Prim. accession # Q7VU52 Identities = 124/266 (46%) Prediction: Non-secretory protein Signal peptide probability: 0.000 Number of predicted TMHs: 0; High confidence in function and specificity.
 
 
0.873
azo3685
Putative hybrid sensor and regulator protein, MmoS) InterPro: IPR003594; ATPbind_ATPase. IPR005467; His_kinase. IPR003661; His_kinA_N. IPR008207; Hpt. IPR001610; PAC. IPR000700; PAS-assoc_C. IPR000014; PAS_domain. IPR001789; Response_reg. Pfam: PF02518; HATPase_c. PF00512; HisKA. PF00785; PAC. PF00989; PAS. PF00072; Response_reg. SMART: SM00387; HATPase_c. SM00388; HisKA. SM00073; HPT. SM00086; PAC. SM00091; PAS. SM00448; REC. TIGRFAM: TIGR00229; sensory_box. TMHMM reporting 2 transmembrane helices; Family membership.
    
 0.838
azo1817
Conserved hypothetical two-component hybrid sensor and regulator. Homology to ebA6890 of Azoarcus sp. EbN1 of 56% (gnl|keqq|eba:ebA6890(KEGG)). InterPro: IPR003594 ATPbind_ATPase. IPR004358 Bact_sens_pr_C. IPR005467 His_kinase. IPR003661 His_kinA_N. IPR009082 His_kin_homodim. IPR001610 PAC. IPR000700 PAS-assoc_C. IPR000014 PAS_domain. IPR001789 Response_reg. Pfam: PF02518 HATPase_c. PF00512 HisKA. PF00785 PAC. PF00989 PAS. PF00072 Response_reg. SMART: SM00387 HATPase_c. SM00388 HisKA. SM00086 PAC. SM00091 PAS. SM00448 REC. TIGRFAM: TIGR00229 sensory_box; 3 TMHMM reporting 7 transmembra [...]
    
 0.824
azo1986
Conserved hypothetical protein; Entry name TREMBL:Q89PQ1 Prim. accession # Q89PQ1 Identities = 241/381 (63%) Thiolase, N-terminal domain (Pfam predicted) Prediction: Non-secretory protein Signal peptide probability: 0.00 Number of predicted TMHs: 0.
 
 0.806
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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