STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azo1944Conserved hypothetical protein. Homology to mll3445) of M. loti of 71% (trembl|Q98G8). InterPro: Bacterial luciferase (IPR002103). Pfam: Luciferase-like monooxygenase. no signal peptide. no TMHS. (376 aa)    
Predicted Functional Partners:
hpaC
Probable HPA reductase; Putative flavin:NADH reductase ycdH (EC 1.6.8.-). Catalyzes the reduction of free flavins (FMN FAD and riboflavin) by NADH (By similarity). TREMBL:Q8RLG2: 41% identity, 60% similarity InterPro: Flavin reductase-like domain InterPro: IPR002563; Flavin_Reduct. IPR009002; FMN_binding. Pfam PF01613; Flavin_Reduct gmhA: phosphoheptose isomerase No signal peptide Absence of transmembrane helices; Function unclear.
 
 
 0.940
carBb2
Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB); High confidence in function and specificity.
  
  
  0.816
vanB2
Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 42% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding domain; 2Fe-2S iron-sulfur cluster binding domain no signal peptide no TMHs; Family membership.
  
  
 0.774
chrR
Probable chromate reductase. Homology to chrR of E. coli of 49% (tremblnew|AAK62985). Reduction of chromate (Cr(VI)) to Cr(III).no no signal peptide no TMHs; High confidence in function and specificity.
  
 0.745
carBb1
Putative dioxygenase hydroxylase large component; Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation. 81% simialr to a Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBb. Involved in the aerobic degradation of carbazole by Pseudomonas resinovorans sp. strain CA10. TREMBL:Q8GI28 InterPro:IPR005806; Rieske_reg.IPR001663; Ring_hydroxyl_A. Pfam:PF00355; Rieske; 1. PF00848; Ring_hydroxyl_A; [...]
  
  
  0.744
carBa1
Putative dioxygenase, hydroxylase small component; Ring hydroxylating dioxygenases are multicomponent 1,2-dioxygenase complexes that convert closed-ring structures to non-aromatic cis-diols. The beta subunit is may be responsible for the substrate specificity of the enzyme. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyY: Benzene 12-dioxygenase beta subunit (EC 1.14.12.3), involved in benzoate degradation.Degradation of benzoate to 2-hydro-12-dihydroxybenzoate (dhb).; Conserved hypotheti [...]
  
  
  0.741
carBa2
Putative dioxygenase, hydroxylase small component; Hydroxylase large component of 1,2-dioxygenase protein complex, involved in aromatic compounds degradation. Putative 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase, CarBa. Involved in the aerobic degradation of carbazole by P.resinovorans sp. strain CA10. XlyX: Benzoate 12-dioxygenase alpha subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). Benzoate 12-dioxygenase beta subunit (EC 1.14.12.10). DEGRADATION OF BENZOATE TO 2-HYDRO-12-DIHYDROXYBENZOATE (DHB). THE BETA SUBUNIT MAY BE RESPONSIBLE FOR THE SUBST [...]
  
  
  0.736
vanB1
Probable vanillate O-demethylase oxidoreductase (Vanillate degradation ferredoxin-like protein). Homology to vanB of P. sp HR199 of 40% (sprot|VANB_PSEUH). The vanillate demethylase (EC:1.14.13.82) consists of two proteins: an oxygenase and an oxygenase reductase (VanA and VanB). This enzyme is involved in the vanillate degradation, a key intermediate in the degradation of lignin. InterPro: NADH:cytochrome b5 reductase (CBR)(IPR001834); Ferredoxin (IPR001041); Oxidoreductase FAD and NAD(P) binding domain (IPR001433) Pfam: Oxidoredutase FAD-binding domain; Oxidoreductase NAD-binding dom [...]
  
  
 0.733
azo1121
This is a family of hydrolase enzymes. Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoatesynthase catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, TREMBL:Q9HZE2 (34% identity); TREMBL:Q8XSM9 (39% identity). Pfam (PF00857): Isochorismatase family; Family membership.
 
 
 0.730
azo3384
Putative aliphatic sulfonates binding protein precursor.PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM FOR ALIPHATIC SULFONATES. PUTATIVE BINDING PROTEIN. 22% SBP_bac_3. SMART: SM00062; PBPb; 1; Specificity unclear.
  
 
 0.649
Your Current Organism:
Azoarcus sp. BH72
NCBI taxonomy Id: 62928
Other names: A. sp. BH72
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